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Drug Side Effects Flashcards

1
Q

Flushing

A
  • -Vancomycin
  • -Niacin
  • -Adenosine
  • -Dihydropyridine calcium channel blockers
  • -Echinocandins
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2
Q

Coronary vasospasm

A
  • -Cocaine
  • -Amphetamines
  • -Triptans
  • -Ergotamine
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3
Q

Dilated cardiomyopathy

A

–Doxorubicin
–Daunorubicin
(Prevent with dexrazoxane)

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4
Q

Torsades de pointes

A
  • -Potassium channel blockers (class III)
  • -Sodium channel blockers (class IA)
  • -Macrolides
  • -Haloperidol
  • -TCAs
  • -Antiemetics (ondansetron)
  • -Protease inhibitors
  • -Chloroquine
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5
Q

Thrombocytopenia

A
  • -Heparin

- -Cimetidine

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6
Q

Agranulocytosis

A
  • -Clozapine
  • -Carbamazepine
  • -Colchicine
  • -Propylthiouracil
  • -Methimazole
  • -Dapsone
  • -Ganciclovir
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7
Q

Aplastic anemia

A
  • -Chloramphenicol
  • -Benzene
  • -NSAIDs
  • -Propylthiouracil
  • -Methimazole
  • -Carbamazepine
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8
Q

Gray baby syndrome

A

Chloramphenicol

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9
Q

Hemolysis in G6PD deficiency

A
  • -Isoniazid
  • -Sulfonamides
  • -Primaquine
  • -Aspirin (high dose)
  • -Ibuprofen
  • -Nitrofurantoin
  • -Dapsone
  • -Fava beans
  • -Naphthalene
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10
Q

Direct-Coombs positive hemolytic anemia

A
  • -Methyldopa

- -Penicillin

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11
Q

Thrombosis

A
  • -OCPs

- -Hormone replacement therapy

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12
Q

Megaloblastic anemia

A
  • -Phenytoin
  • -Methotrexate
  • -Sulfa drugs
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13
Q

Hot flashes

A
  • -Tamoxifen

- -Clomiphene

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14
Q

Hypothyroidism

A
  • -Amiodarone
  • -Lithium
  • -Sulfonamides
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15
Q

Pulmonary fibrosis

A
  • -Amiodarone
  • -Bleomycin
  • -Busulfan
  • -Methotrexate
  • -Nitrofurantoin
  • -Carmustine
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16
Q

Dry cough

A

–ACE inhibitors

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17
Q

Anticholinergic effects

A
  • -Atropine
  • -TCAs
  • -H1 blockers
  • -Low potency neuroleptics
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18
Q

Disulfiram-like reaction

A
  • -Metronidazole
  • -Certain cephalosporins
  • -Procarbazine
  • -1st generation sulfonylureas
  • -Disulfiram
  • -Griseofulvin
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19
Q

Nephrotoxicity + Neurotoxicity

A
  • Aminoglycosides
  • -Cisplatin
  • -Polymyxin
  • -Loop diuretics
  • -Vancomycin
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20
Q

Sulfa drugs

A
  • -Sulfonamide antibiotics
  • -Sulfasalazine
  • -Probenecid
  • -Furosemide
  • -Acetazolamide
  • -Celecoxib
  • -Thiazides
  • -Sulfonylureas
21
Q

Pseudomembranous colitis

A
  • -Clindamycin
  • -Amoxicillin/ampicillin
  • -Cephalosporins
22
Q

Hepatic necrosis

A
  • -Halothane
  • -Acetaminophen
  • -Valproic acid
  • -Amanita phalloides
23
Q

Hepatitis

A
  • -Rifampin
  • -Isoniazid
  • -Pyrazinamide
  • -Statins
  • -Fibrates
24
Q

Tertiary adrenal insufficiency

A

–Corticosteroid withdrawal

25
Q

Gynecomastia

A
  • -Spironolactone
  • -THC (marijuana)
  • -Alcohol (chronic use)
  • -Cimetidine
  • -Ketoconazole
  • -Estrogens
  • -Digoxin
26
Q

Gout

A
  • -Diuretics (loop and thiazide)
  • -Niacin
  • -Cyclosporine
  • -Pyrazinamide
27
Q

Gingival hyperplasia

A
  • -Phenytoin
  • -Verapamil
  • -Cyclosporine
28
Q

Osteoporosis

A
  • -Corticosteroids

- -Chronic heparin

29
Q

Photosensitivity

A
  • -Sulfonamides
  • -Amiodarone
  • -Tetracycline
  • -5-FU
30
Q

Steven-Johnson Syndrome

A
  • -Carbamazepine
  • -Lamotrigine
  • -Allopurinol
  • -Phenytoin
  • -Penicillin
  • -Phenobarbital
  • -Anti-epileptic drugs
  • -Sulfa drugs
31
Q

Drug-induced lupus

A
  • -Sulfonamides
  • -Hydralazine
  • -Isoniazid
  • -Procainamide
  • -Phenytoin
  • -Etanercept
32
Q

Tendinitis/cartilage damage

A

–Fluorquinolones

33
Q

Interstitial nephritis

A
  • -NSAIDS
  • -Furosemide
  • -Antibiotics (Methicillin)
34
Q

Diabetes insipidus

A
  • -Lithium

- -Demeclocycline

35
Q

Fanconi syndrome

A
  • -Tetracycline (expired)
  • -Ifosfamide
  • -Heavy metal exposure/Wilson disease
36
Q

Hemorrhagic cystitis

A
  • -Cyclophosphamide

- Ifosfamide

37
Q

Parkinson-like syndrome

A
  • -Metoclopramide
  • -Antipsychotics
  • -Reserpine
38
Q

Cinchonism (dizziness, headache, vision changes, tinnitus)

A
  • -Quinidine

- -Quinine

39
Q

Seizures

A
  • -Bupropion
  • -Imipenem/cilastatin
  • -Tramadol
  • -Metoclopramide
  • -Isoniazid (Vit B6 deficiency)
  • -Enflurane
40
Q

Tardive dyskinesia

A
  • -Antipsychotics

- -Metoclopramide

41
Q

SIADH

A
  • -Carbamazepine
  • -Cyclophosphamide
  • -SSRIs
42
Q

Myopathy

A
  • -Fibrates
  • -Niacin
  • -Colchicine
  • -Hydroxychloroquine
  • -IFN-alpha
  • -Penicillamine
  • -Statins
  • -Glucocorticoids
43
Q

Teeth discoloration

A

–Tetracyclines

44
Q

Fat redistribution

A
  • -Protease inhibitors

- -Glucocorticoids

45
Q

Hyperglycemia

A
  • -Tacrolimus
  • -Protease inhibitors
  • -Niacin
  • -Hydrochlorothiazide
  • -Corticosteroids
46
Q

Acute cholestatic hepatitis, jaundice

A

–Erythromycin

47
Q

Diarrhea

A
  • -Acamprosate
  • -Acarbose
  • -Cholinesterase inhibitors
  • -Colchicine
  • -Erythromycin
  • -Ezetimibe
  • -Metformin
  • -Misoprostol
  • -Orlistat
  • -Pramlintide
  • -Quinidine
  • -SSRIs
48
Q

Pancreatitis

A
  • -Didanosine
  • -Corticosteroids
  • -Alcohol
  • -Valproic acid
  • -Azathioprine
  • -Diuretics (Furosemide, hydrochlorothiazide)
49
Q

Pill-induced esophagitis

A
  • -Tetracyclines
  • -Bisphosphonates
  • -Potassium chloride

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