toxidrome Flashcards
1
Q
what medications can potentially cause serotonin syndromes
A
opioid
antidepressant
MAOI
SJW
lithium
2
Q
sx of serotonin syndrom (CNS)
A
insomnia
anxiety
agitation
confusion
coma
3
Q
sx for serotonin syndrome (autonomic)
A
mydriasis (pupil dilation)
hyperthermia
tachycardia
flushing
diaphoresis
diarrhoea
4
Q
sx for serotonin syndrome (neuromuscular)
A
hyperreflexia
clonus (spontaneous / inducible / ocular)– involuntary and rhythmic muscle contractions
shivering
tremor
hypotonia
rigidity
5
Q
management for mild sx
A
reduce or cease the agent
6
Q
moderate sx
A
diazepam
cryproheptadeine (antihistamine)
7
Q
severe sx
A
chlorpromazine
8
Q
if NO serotonergic agent was inteoduced 5 days before—still be can diagononised w serotonin syndrome Y/N
A
N