toxidrome Flashcards

1
Q

what medications can potentially cause serotonin syndromes

A

opioid
antidepressant
MAOI
SJW
lithium

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2
Q

sx of serotonin syndrom (CNS)

A

insomnia
anxiety
agitation
confusion
coma

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3
Q

sx for serotonin syndrome (autonomic)

A

mydriasis (pupil dilation)
hyperthermia
tachycardia
flushing
diaphoresis
diarrhoea

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4
Q

sx for serotonin syndrome (neuromuscular)

A

hyperreflexia
clonus (spontaneous / inducible / ocular)– involuntary and rhythmic muscle contractions
shivering
tremor
hypotonia
rigidity

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5
Q

management for mild sx

A

reduce or cease the agent

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6
Q

moderate sx

A

diazepam
cryproheptadeine (antihistamine)

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7
Q

severe sx

A

chlorpromazine

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8
Q

if NO serotonergic agent was inteoduced 5 days before—still be can diagononised w serotonin syndrome Y/N

A

N

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