Toxicology Flashcards
Anticholinergics
HR and BP increases No change in resp Temperature increases Pupils dilate Decreased bowel sounds Dry
Cholinergic
no chnage in HR/BP/Resp/Temp
Pin point pupils
Bowel sounds
Wet?
Opioid
decreased HR, Resp Cold Pin point pupils Increased bowel sounds ?
Sympathopimimetic
increases HR, respiratory, temperature
dialted pupils
bowel sounds audible
Sedative hypnotic
low HR, low resp, low temperature
SUPPORTIVE CARE- FAST HUGS IN BED PLEASE
Fluids Analgesia Sedation Thromboprophylaxis Head up Ulcer prophylaxis Glucose contorl Skin control In catheter, NG tube Temperature Psychological
ANTI DOTES:
- paracetemol
- atropine
- ca2+ blockes
- iron
- cyanide
- benzodiazpines
- beta blockers
- ethylene glycol
- local anaesthetic
- opioids
- metHb
- digoxin
- seretoinin
- TCA’s
- warfarin
- heparin
- paracetemol= N-acetyl cystine
- atropine= organophosphates
- ca2+ blockers= Caclium chloride
- iron= desferioxamine
- cyanide= hydroxocabalamin
- benzodiazepines= flumenazil
- beta blockers= glucagon
- ethylene glycol= fomepizole
- local anaesthetic= intralipid
- opioids= naloxene
- MetHb= methylene blue
- digoxin= digibind
- seretonin= cyprohepatidine
- TCA’s= NaHCO3
- warfarin= vitamin K
- heparin= protamine sulphate
organophosphate poisoning
pinpoint pupils
drowsy
respiratory depression
beta-blocker OD
bradycardia drowsy confusion seizure hallucination dilated pupils coma bronchospasm
cocaine
tachycardia mydriasis diaphoresis hyperthermia chest pain-MI, arrhythmias, aortic dissection.
Paracetamol:
Activated Charcoal
Aspirin
Heroin/Opioids
Benzodiazepines
Tricyclic Antidepressants:
Lithium
Warfarin
Heparin
Paracetamol:
Within 1st hour give
Activated Charcoal
N-acetylcysteine
Aspirin
Haemodialysis
Heroin/Opioids
Naloxone
Benzodiazepines
Flumazenil
Tricyclic Antidepressants:
IV Bicarbonate
Lithium
Dilute with Saline or Haemodialysis
Warfarin
Vitamin K
Heparin
Protamine sulfate
Beta Blockers
Methanol
Digoxin
Carbon Monoxide
Cyanide
Lead
Beta Blockers
Atropine- fertiliser inhalation/ drinking by farmers child
Methanol
Fomepizole
Ethanol
Digoxin
Digibind
Carbon Monoxide
High O2 & hyperbaric O2
Cyanide
Hydrocabalamine
Lead
Dimercaprol