Neurodegenerative + demyelinating diseases

Question 1

dementias

Answer 1

cortically based disease (alzheimers, levy body)

Question 2

ataxic disorders

Answer 2

predominantly effects the cerebellum (spinocerebellar ataxic)

Question 3

kinetic rigid diseases

Answer 3

affects the substantial nigra
parkinson disease
supra nuclear gaze palsy

Question 4

hyperkinetic movement

Answer 4

affects basal ganglia

huntington disease

Question 5

motor neurone disease

Answer 5

affects upper and lower motor neurone pathways

x linked spinobulbar muscular atrophy
spinal muscular atrophy
hereditary spastic paraparesis

Question 6

demyelinating disorders

Answer 6

destruction of normal myelin with relative preservation of axons

• MS
• ADEM
• acute haemorrhage leuoencephalopathy
• PML
• central pontine myelinosis
• *trigeminal neuralgia (due to compressing blood vessels surrounding the nerves)