Toxicology Flashcards
Toxicity
Damage due to high dose or sensitivity
What is therapeutic index equation
How safe a drug is
LD50/ ED50
5 routes of toxic entry
Ingestion Sub cutaneous Injection Ocular Inhaled
What does the veterinary poison information service do
Provides info
Educates
Carries out toxic labs
Antidotes
Most commons toxins (3)
NSAIDs
Anticoagulant
Chocolate
How to treat toxin (3)
Treat symptoms
- HR respiration temperature
Prevent continual absorption
Antidote
How can you prevent continual absorption
Gastric evacuation
Wash
Gastric lavage
Absorbent
Elimination
Chemicals for gastric evacuation(4)
Hydrogen peroxide
Apomorphine
Xylazine
When can you not induce gastric emptying
Seizures Coma Abdominal surgery Hypoxia Horses
Corrosive item ingested
How much is removed from vomittung
60^
How can you further remove toxin
Absorbent a
No chemical reaction
Activated charcoal
What are cathartic
Speed up transit time in gut
Sodium
Magnesium sulphate
Sorbitol
Cheating agents
Bind metal ions thus prevent poison as chemically inert
EDTA
Poison
Substance which may destroy life or injure health
