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Critical Care > Toxicology > Flashcards

Toxicology Flashcards

1
Q

Bradycardia
Hypotension
Somnolence
Miosis

Management

A

Clonidine overdose
(Central alpha 2 agonist)

Supportive (naloxone for severe cases)

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2
Q

Stages of acetaminophen toxicity

A

1) < 24 hours. N/V, anorexia, malaise. HypoK. Met acidosis
2) 24-72 hrs. Abd pain, hepatic tenderness.
3) 72 hrs. Fulminant hepatic failure. Encephalopathy. Elevated AST/ALT, Bili, PT. Coagulopathy, AKI, met acidosis, pancreatitis.
4) > 5 days. Recovery or MOD

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3
Q

Evidence of cardiotoxicity in Bupropion overdose

A

Prolonged QTc or QRS

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4
Q

Management for methemoglobinemia

A

Methylene blue

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5
Q

CNS and respiratory depression
Seizures
Hypoglycemia

A

Ethylene glycol poisoning

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6
Q

Necrotic lesions
Vomiting
Fever/Chills
Myalgias
Fatal hemolysis

A

Cutaneous-hemolytic loxoscelism

Brown recluse spider bite

Sphingomyelinase D - toxin mediated hemolysis

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7
Q

Management for pit viper envenomation

A

Crotalidae polyvalent immune fab

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8
Q

Most common cause of death in tetanus

A

Autonomic instability
Hospital-acquired pneumonia

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Critical Care (13 decks)

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