Nephrology Flashcards
Management for moderate/severe hypermagnesemia
Lasix + fluid bolus
Sodium correction in hyperglycemia
+ 1.6 mEq/L sodium for every 100 mg/dL increase in serum glucose.
Corrected Na = measured Na + ((BG - 100)/100) x 1.6
Effect of atrial natriuretic peptide on kidneys
Inhibits activity of RAAS
decreases afferent arteriolar resistance
Increased renal blood flow
Fractional excretion of Urea
(Urine Urea x Serum Cr)/(serum Urea x urine Cr) x 100
< 30% = prerenal
> 70% = intrarenal
Diffusion in CRRT
Particles move from area of high concentration to low contraction
Convection in CRRT
Particles move across a member via pressure gradient
FeNa
((UrNa x sCr)/(sNa x UrCr)) x 100
< 1% = prerenal
> 2% = ATN
Transfer of solute across a semipermeable membrane by pressure-induced water flow (convection)
Hemofiltration
Preferred for higher molecular weight solutes and for removal of water
Transfer of solute across a semipermeable membrane alone concentration gradient using countercurrent flow for optimal efficiency (diffusion)
Hemodialysis
Preferred for smaller solutes
(Cr, urea, electrolyte, acid/base buffers)
Possible causes of AKI in rhabdomyolysis
1) decreased renal perfusion
2) tubular case formation
3) direct toxic effect of myoglobin on renal tubules
Sodium deficit
(Target Na - Measured Na) x 0.6 x wt