Toxicity and Side Effects II Flashcards

1
Q

myopathy drugs

A
fibrates
niacine
colchicine
hydroxychloroquine
IFN-a
penicillamine
statin
glucocorticoids
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2
Q

osteoporosis drugs

A

corticosteroids

hemarin

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3
Q

photosensitivity drugs

A

sulfonamides
amiodarone
tetracyclines
5-FU

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4
Q

SJS drugs

A

anti-epileptics (not lamotrigine)
allopurinol
sulfa drugs
PCN

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5
Q

SLE like syndrome drugs

A
sulfa
hydralazine
isoniazid
procainamide
phenytoin
etanercept
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6
Q

teeth discolor drug

A

tetracycline

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7
Q

tendon rupture and cartilage damage drug

A

FQs

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8
Q

cinchonism drug

A

tinnitus and deaf with sight issues

quinidine
quinine

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9
Q

parkinson like syndrome drugs

A

antipsychotics
reserpine
metoclopramide

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10
Q

seizure drug rxns

A

isoniazid - B6 deficient
bupropion
imipenem
enflurane

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11
Q

tardive dyskinesia

A

long term tx
-antipsychotics
metoclopramide

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12
Q

diabetes insipidus rxn

A

lithium

demeclocycline

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13
Q

fanconi syndrome

A

with expired tetracycline

malfunction kidney tubules

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14
Q

hemorrhagic cystitis

A

cyclophosphamide
ifofsamide
tx - mesna

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15
Q

interstitial nephritis drugs

A

methicillin
NSAID
furosemide

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16
Q

SIADH drugs

A

carbamazepine
cyclophosphamide
SSRI

17
Q

dry cough

A

ACE I

18
Q

pulmonary fibrosis

A

bleomycin
busulfan
methotrexate
amiodarone

19
Q

antimuscarinic agent

A

atropine
TCA
H1 blocker
antipsychotic

20
Q

disulfiram like rxn

A
metrondiazole
certain cephalosporins
griseofulvin
procarbazine
1st gen sulfonylurea
21
Q

cisplatin toxicity

A

respond to amifostine

22
Q

P450 inducers

A
chronic alcohol
st john wort
phenytoin
phenobarbitol
nevirapine
rifampin
griseofulvin
carbamazepine

chronic alcoholics steal phen-phen and never refuse greasy carbs

23
Q

P450 inhibitors

A
acute alcohol abuse
ritonivir
amiodarone
cimetidine
ketoconazole
sulfonamide
isoniazid
grapefruit juice
quinidine
macrolide (not azithro)

AAA RACKS IN GQ Magazine

24
Q

substrate for P450

A

anti-epileptics
theophylline
warfarin
OCPs

25
Q

sulfa drugs

A
probenecid
furosemide
acetazolamide
celecoxib
thiazide
sulfonamide antibiotics
sulfasalazine
sulfonylureas

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