Toxicities - Antidotes Flashcards by Saloni Malik

Q

Acetaminophen

A

N-acetylcysteine (replenishes glutathione)

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Q

AchE inhibitors, organophosphates

A

Atropine > pralidoxime

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Q

Amphetamines

A

Amphetamines are basic, give NH4Cl - acidify the urine

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Q

Antimuscarinic, anticholinergic agents

A

Physostigmine salicylate, control hyperthermia

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Q

Benzodiazapines

A

Flumenazil

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Q

B-blockers

A

Glucagon

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Q

Carbon monoxide

A

100% O2, hyperbaric O2

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Q

Copper, arsenic, gold

A

penicillamine

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Q

Cyanide

A

Nitrite + thiosulfate, hydroxyocobalamin

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Q

Digitalis

A

Anti-dig Fab fragments

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Q

Heparin

A

Protamine

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Q

Iron

A

deFEroxamine, deFErasirox

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Q

Lead

A

EDTA, dimercaprol, succimer, penicillamine

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Q

Mercury, arsenic, gold

A

diMERcaprol (BAL), succimer

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Q

Methanol, ethylene glycol

A

Fomepizole > ethanol, dialysis

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Q

Methemoglobin

A

Methylene blue

Q

Opioids

A

naloxone, naltrexone

Q

salicylates

A

sodium bicarb (alkalinize urine)

Q

TCAs

A

sodium bicarb (plasma alkalinization)

Q

tPA, streptokinase, urokinase

A

Aminocaproic acid

Q

Warfarin

A

Vitamin K (delayed effect), FFP (immediate)