Muscarinic antagonists Flashcards
What three muscarinic antagonists act on the eye?
atropine, homatropine, tropicamide
What are the effects of atropine, homatropine, and tropicamide?
Produce mydriasis and and cycloplegia.
Which organ system is benztropine typically given for?
CNS.
What are the applications of benztropine?
Parkinson disease, acute dystonia.
Which organ system is glycopyrrolate typically given for?
GI, respiratory
What are the applications of glycopyrrolate?
IV: pre-op to reduce GI secretions
PO: Drooling, peptic ulcer
Which organ system is hyoscyamine and dicyclomine typically given for?
GI
What are the applications of hyoscyamine and dicyclomine?
Antispasmodics for IBS.
Which organ system is ipratropium and tiotropium typically given for?
Respiratory
What are the applications of ipratropium and tiotropium?
COPD, Asthma
Which organ system is oxybutynin, solifenacin, and tolterodine typically given for?
GU
What are the applications of oxybutynin, solifenacin, and tolterodine?
Reduce bladder spasms and urge urinary incontinence (overactive bladder)
Which organ system is scopalamine typically given for?
CNS
What are the applications of scopalamine?
Motion sickness.
What is an “urgent” indication for atropine?
Bradycardia.