Sympathomimetics Flashcards
Which receptors do albuterol and salmeterol target?
B2 > B1
What are the applications for albuterol and salmeterol?
Albuterol for acute asthma, salmeterol for long-term asthma or COPD control.
Which receptors does dobutamine target?
B1 > B2 > alpha
What are the applications for dobutamine?
heart failure (inotropic > chronotropic), cardiac stress testing
Which receptors does dopamine target?
D1 = D2 > B > alpha
What are the applications for dopamine?
Unstable bradycardia, HF, shock
Which effects of dopamine predominate at high doses?
Inotropic and chronotropic alpha effects
Which receptors does epinephrine target?
B > alpha
What are the applications for epinephrine?
Anaphylaxis, asthma, open-angle glaucoma. Alpha effects predominate at high doses.
Which has stronger B2 action, epi vs. noepi?
Epi is significantly stronger.
Which receptors does isoproterenol target?
B1 = B2
What are the applications for isoproterenol?
Electrophysiologic evaluation of tacharrythmias. Can worsen ischemia.
Which receptors does norepinephrine target?
a1 > a2 > B1
What are the applications for norepinephrine?
Hypotension (septic shock). *Decr renal perfusion.
Which receptors does phenylephrine target?
a1 > a2