Toxic Injuries

Question 1

most common site of CNS atrophy in alcoholic?

Answer 1

superior vermis of the cerebellum

Question 2

What do you give to a pt with organophosphate poisoning?

what should you definitely not give because it will make it worse?

Answer 2

Atropine with pralidoxime

dont give methacholine (cholinergic) or Pyridostigmine/physostigmine/edrophonium (cholinesterase inhibitors)

Question 3

what would you expect with mercury poisoning?

Answer 3

symptoms similar to Mad Hatter: Mood swings, nervousness, irritability, tremor, ataxia

extensive damage to cerebellum and calcarine cortex of occipital lobe

Question 4

what scenario do you expect to see chronic ergotism (ergot poisoning)

Answer 4

person from undeveloped country with diet high in breads with rye

develop degeneration of posterior column and neuropathy

Question 5

pt who works in a mine develops parkinsonism - what poisoning do you suspect?

Answer 5

Manganese

Question 6

Person ingests a reef fish from tropics and develops abdominal discomfort, N/V/D, followed by paresthesia, headache and fatigue. What do you suspect?

Answer 6

Ciguatera food poisoning

Question 7

excessive Ionizing radiation may produce accelerated what? causing increased stroke risk

Answer 7

atherosclerosis

may lead to carotid stenosis and strokes

stem had hodgkins pt with recent stroke and asked etiology-supposed to link hx of hodgkin with radiation causing the bilateral carotid bruit and stroke