Movement Disorders Flashcards

1
Q

What drugs may unmask an underlying chorea (huntingtons)

A

Dopaminergic drugs (L-dopa, bromocriptine, and lisuride)

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2
Q

Tardive dyskinesia may be a side effect of what drug used to suppress chorea in parkinsons

A

haloperidol

and other dopamine antagonists

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3
Q

What recreational drug of abuse may cause rapid development of Parkinsonism

A

MTPT

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4
Q

Trihexyphenidyl has what mechanism of action? why is it used in Parkinsonism?

A

anticholinergic

used to decrease signs of parkinsonism caused drugs that interfere with dopamine neurotransmission. (offending medication should also be slowly tapered off too)

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5
Q

What medications are used to treat Torettes?

A

Haloperidol, pimozide, trufluoperazine, and fluphenazine.

anti-epileptics such as carbamazepine and phenytoin are not useful

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6
Q

What is Meige syndrome?

what drug can produce the features of Meige syndrome?

what is a common treatment

A

focal dystonia characterized by blepharospams, forceful jaw opening, lip retraction, neck contractions, and tongue thrusting.

sometimes brought on by phenothiazine or butyrophenone

botox injections

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7
Q

what’s another name/description for Wilson’s disease?

how does it affect the kidney/liver?

A

Hepatolenticular degeneration

renal tubular acidosis occurs as well as hepatic fibrosis–>hepatic failure

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8
Q

In vegetative state what brain structures are injured and what remains intact?

A

cortex is injured and brainstem remains intact

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9
Q

combo of increased calcium, fatigue, weakness, and pseudogout in an elderly patient should raise suspicion of what?

A

Primary hyperparathyroidism.

even if calcium levels are normal with these symptoms, PTH may be elevated

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