TOX 9 - Insecticides

Question 1

Chlorinated hydrocarbon insecticides

Answer 1

Acute rare, chronic more common

Inactivates Na+ in excitable membranes

Half life over 1 year, extremely slow elimination

Question 2

Organophosphorus insecticides effect and absorption

Answer 2

Irreversible cholinesterase inhibitors

Absorbed in skin, GI, resp. tract

Causes muscarinic excess

Question 3

Organophosphorus insecticides treatment

Answer 3

oxime-agents

maintenance of vital organs

decontamination

atropine

Question 4

Carbamate insecticides

Answer 4

Reversible cholinesterase inhibitors

Shorter effect than organophosphorus type

Treatment is the same as organophosphorus insecticides

Question 5

Nicotine

Answer 5

Well absorbed, incl. across skin

Toxic effects - CNS (resp. arrest, convulsions, coma) depolarizing SkM end plate blockade

Symptomatic treatment

Question 6

Other natural insecticides

Answer 6

Rotenone

Pyrethrum