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Toxicology Semmelweis > TOX 8 - Glycols and aldehydes > Flashcards

TOX 8 - Glycols and aldehydes Flashcards

1
Q

Glycol toxicity

A

Nephrotoxicity - tubular necrosis
Hepatotoxic
Narcotic effect

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2
Q

Glycol therapy

A

No specific antidote

Gastric lavage with potassium permanganate

Symptomatic therapy against kidney damage

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3
Q

Aldehydes

A

Formaldehyde
Acetaldehyde
Paraldehyde
Metaldehyde

(FAP M(ore)?)

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4
Q

Formaldehyde effects and therapy

A

protein precipitation -> necrosis

therapy consists of decontamination, supportive therapy and gastric lavage

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5
Q

Acetaldehyde

A

Weak local irritable effect, cause necrosis

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6
Q

Paraldehyde

A

Not toxic

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7
Q

Metaldehyde

A

Metabolized into acetaldehyde

Causes local irritation (hemorraghic gastritis) and later CNS effects

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Toxicology Semmelweis (15 decks)

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