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..EM Board Review > Tox > Flashcards

Tox Flashcards

1
Q

beta blocker OD that would cause seizure

A

propanolol

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2
Q

antidote to sarin gas most effective if given within 4-6 hours of exposure

A

pralidoxime

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3
Q

headache, blurry vision, papilledema, hair loss, pruritic skin, person overdosing on what?

A

Vitamin A

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4
Q

possible kerosene or hydrocarbon ingestion, pt asymptomatic, next step

A

obs 6 hours and do chest XR at 6 hours

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5
Q

valproic acid toxicity treatment

A

L carnitine

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6
Q

weird side effect of phenytoin

A

gingival hyperplasia

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7
Q

lead poisoning antidote

A

dimercaprol

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8
Q

eating fish, hot and cold sensation seem to be off - dx?

A

ciguatera tox

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9
Q

treatment of salicylate tox

A

sodium bicarb

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10
Q

retinal hyperemia - what ingestion and causes what acid build up?

A

methanol, formic acid build up

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11
Q

oxymetazoline/flonase OD can present as what other drug

A

clonidine

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12
Q

blurred vision, bradycardia, EKG with hyperK and peaked T waves - what toxicity

A

digoxin

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13
Q

patient develops HIT on heparin, next step

A

stop heparin and start direct thrombin inhibitor, bivalirudin

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14
Q

tx for cardiac arrest in digoxin overdose

A

10 vials of digoxin specific antibody

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15
Q

serious complication of lithium toxicity

A

arginine vasopressin resistance (nephrogenic DI)

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16
Q

what cofactor should be supplemented in ethylene glycol poisoning?

A

thiamine

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17
Q

what recreational drug can contribute to seratonin syndrome

A

MDMA/ectasy

18
Q

what blood lead level indicates the need for chelation therapy with dimercaprol in asymptomatic child?

A

70 ug/dL

19
Q

OD - pH 7.2, PaCO2 at 20, HCO3 at 12

A

salicylate tox

20
Q

what acid base disturbance do you see first in salicylate tox

A

early respiratory alkalosis

21
Q

what is the active metabolite in acetaminophen toxicity

A

N-acetyl-p-benzoquinoneimine (NAPQI)

22
Q

ketosis without a wide anion gap metabolic acidosis

A

isopropyl alcohol (rubbing alcohol)

23
Q

30 min after TCA overdose, sinus tach, next treatment

A

activated charcoal

24
Q

treatment of SLUDGE and DUMBBELLS

A

atropine, then pralidoxime (2 PAM)

25
Q

what is contraindicated in hydrocarbon toxicity

A

amiodarone

26
Q

physostigmine side effect?

A

profound bradycardia, seizures, asystole

27
Q

drug often with eliquis that can cause increased plasma concentration of eliquis

A

diltizem

28
Q

hypernatremia and lithium toxicity, treatment/

A

hemodialysis - nephrogenic DI

29
Q

ingestion, + ketones, elevated Cr, but normal BUN, no AGAP

A

isopropyl alcohol

30
Q

2-8 weeks after iron overdose, what dx?

A

bowel obstruction, pyloric stenosis

31
Q

what reverses dabigatran (direct thrombin inhibitor)

A

Idarucizumab (monoclonal antibody fragment)

32
Q

high anion gap acidosis without lactic or ketone elevation, ingested what?

A

ethylene glycol

33
Q

accidental hydrocarbon ingestion, next step

A

obs 6 hours and repeat chest XR

34
Q

finding in chronic digoxin overdose

A

color vision changes

35
Q

treatment for silo fillers disease

A

methylene blue, nitrogen has displaced

36
Q

TCAs act by …

A

fast inward Na channel blockade (class I antidysrrhythmics as well)

37
Q

carbon monoxide toxicity causes a … shift of the oxygen-hemoglobin dissociation curve

A

left shift

38
Q

bidirectional v tach

A

digoxin toxicity

39
Q

mechanism of action of NAC

A

Regenerates sulfhydryl donor glutathione

40
Q

methylene chloride will cause

A

carboxyhemoglobin

41
Q

vomiting and diarrhea after fish, paresthesias and teeth feel loose

A

ciguatera poisoning

..EM Board Review (15 decks)

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