topical Flashcards
Erythema
redness of the skin
Pruritis
a skin disorder attended with itching
Candidiasis
a fungal infection
Tinea
ringworm
AA
Affected area
Crm
Cream
Ung
Ointment
Cmpd
Compound
UD
As directed
PRN
As needed
Lidocaine MOA
Local anesthetic agent
Stabilize neuronal membranes producing an analgesic effect
Lidocaine indications
Treatment/relief of pain
Lidocaine adverse effects
Application site irritation
Lidocaine interactions
Antiarrhythmic agents
Local anesthetics
Lidocaine counseling
Apply to intact skin only; patches may be cut into smaller sizes with scissors before removal of the release liner
Wash hands after handling patch and avoid eye contact
Store and dispose of patches out of the reach of children, pets, and others
Never reuse a patch
Remove patch prior to MRI procedures to avoid burns
Clobetasol, Fluocinonide, Hydrocortisone, Mometasone, Triamcinolone
Topical Corticosteroids MOA
Produces anti-inflammatory, antipruritic, and vasoconstrictor actions
Clobetasol, Fluocinonide, Hydrocortisone, Mometasone, Triamcinolone
Topical Corticosteroids indications
Psoriasis
Dermatitis
Clobetasol, Fluocinonide, Hydrocortisone, Mometasone, Triamcinolone
Topical Corticosteroids adverse effects
Dryness
Burning
Itching
Irritation
Clobetasol, Fluocinonide, Hydrocortisone, Mometasone, Triamcinolone
Topical Corticosteroids counseling
For external use only; do not apply to mucous membranes
Apply in a thin layer
Do not cover treated area unless directed by a physician
Avoid sunlight exposure to affected area
Metronidazole, Mupirocin, Chlorhexidine, Clindamycin
Topical Antibiotics/Antiseptics MOA
Inhibits protein synthesis
Causes cell death in susceptible organisms
Metronidazole, Mupirocin, Chlorhexidine, Clindamycin
Topical Antibiotics/Antiseptics indications
Treatment of acne/rosacea
Treatment of bacterial vaginosis
Metronidazole, Mupirocin, Chlorhexidine, Clindamycin
Topical Antibiotics/Antiseptics adverse effects
Topical: Burning, skin irritation, dryness, headache
Vaginal: Vulva/vaginal irritation, vaginal discharge, fungal infection
Serious: leukopenia
Metronidazole, Mupirocin, Chlorhexidine, Clindamycin
Topical Antibiotics/Antiseptics interactions
Warfarin?
Alcohol?
Metronidazole, Mupirocin, Chlorhexidine, Clindamycin
Topical Antibiotics/Antiseptics patient counseling
For external use only
Avoid contact with eyes or mouth
Wash hands and affected areas before application of gel
Cosmetics can be worn after application of gel
Discontinue use and notify physician if skin rash occurs
Vaginal Product:
Mupirocin MOA
Inhibits protein synthesis in susceptible organisms
Mupirocin indications
Secondary infected skin lesions
Impetigo
Elimination of nasal MRSA
Mupirocin adverse effects
Burning
Stinging
Erythema
Mupirocin counseling
For external use only
Avoid contact with eyes or mouth.
Treated area may be covered with a dressing
Contact provider if no improvement is seen in 3-5 days
Chlorhexidine MOA
Binds to bacterial cell walls and extramicrobial complexes
Bactericidal effect
Chlorhexidine indications
Skin cleanser
Germicidal hand rinse
Chlorhexidine adverse effects
Erythema
Roughness and/or dryness
Sensitization
Chlorhexidine counseling
For external use only
Do not swallow solution
Do not apply to wounds that involve more than superficial layers of skin
Do not use on lumbar puncture sites
Solutions may be flammable
Avoid application to hairy areas, which may significantly delay drying time
Clindamycin MOA
Inhibit protein synthesis by binding to 50S ribosomal subunits
The drug inhibits the growth of susceptible organisms on the surface of the skin and reduces the concentration of free fatty acids in sebum.
Clindamycin indications
Treatment of acne
Treatment of bacterial vaginosis
Treatment of susceptible bacterial infections
Clindamycin adverse effects
Topical: Dryness, burning, itching, scaliness/peeling skin, erythema, oiliness
Vaginal: Vaginal candidiasis, vaginitis, pruritis, vaginal pain
Clindamycin counseling
Patient Counseling (Topical)
Wash hands thoroughly before and after applying
Apply small amount of product to affected area
Wait 30 minutes before shaving or applying makeup after application
Patient Counseling (Vaginal)
Remain lying down for 30 minutes following administration
Avoid intercourse during therapy
Vaginal products may weaken condoms or contraceptive diaphragms
Ketoconazole, Terconazole
Topical Antifungals
Ketoconazole, Terconazole MOA
Disrupts cell wall permeability
Ketoconazole, Terconazole indications
Ketoconazole
Treatment of cutaneous fungal infections
Terconazole
Treatment of uncomplicated vulvovaginal candidiasis
Ketoconazole, Terconazole adverse effects
Ketoconazole
Severe skin irritation, pruritis, stinging
Terconazole
Burning and irritation, itching
Ketoconazole counseling
For external use only; not for ophthalmic, oral, or intravaginal use
Although improvement and symptom relief usually occur quickly, continue to treat for recommended time period
Terconazole counseling
For vaginal use only
Refrain from intercourse during period of treatment - sexual partner may experience penile irritation
Suppositories may cause breakdown of condoms and diaphragms - avoid concurrent use
Finish course of therapy even if symptoms have improved
Vaginal product does not appear to interact with oral contraceptives
