Topic 8 AFPs

Question 1

Method of disrupting ice formation

Answer 1

Binds to ice and creates an uneven surface

Question 2

structure of winter flounder AFP

Answer 2

single 10 turn alpha helix

Question 3

3 Theories of how to ice bind

Answer 3

1) Flat hydrophobic surface binds to ice
2) Waters around AFP will be displaced and will not form ice due to increased entropy
3) Arrangement around hydrophobic surface will create icelike arrangements that will bind to the ice

Question 4

Spruce Budworm AFP structure

Answer 4

β-solenoid (toblerone bar)

3 parallel beta sheets

Question 5

Snowflea AFP structure

Answer 5

6 left handed helices (2x3 arrangement)

with G-x-y repeats