Topic 1 Basics and Intro Flashcards
1
Q
Typical hydrogen bond length
A
2.8Å
2
Q
Free energy equation
A
ΔG = ΔH - T ΔS
negative ΔG is a favourable change
3
Q
Henderson Hasselbach equation
A
pH = pKa + log([A-]/[HA])
4
Q
Deprotonation fraction
A
x= [A-]/([HA]+[A])
or x= [10^(pH-pKa)] / [1+10^(pH-pKa)]
5
Q
Rule for protonation fraction in relation to pH
A
If pH = pKa + 1 : x=0.91
If pH = pKa + 2 : x=0.99
6
Q
Mammalian amino acids are what chirality ?
A
L
7
Q
pKa of Asp / Glu
A
4
8
Q
pKa of His
A
6
9
Q
pKa of Cys
A
8.5
10
Q
pKa of Tyr
A
10.5
11
Q
pKa of Arg
A
12.5
12
Q
N-Cα bond angle name
A
Φ (Phi) bond
13
Q
Cα-C bond angle name
A
Ψ (Psi) bond
14
Q
α-helix pitch
distance between loops
A
approx 5.4Å
15
Q
Φ/Ψ angles of an α-helix
A
Φ=60 Ψ=40 (approx)
