Topic 8 Flashcards
2 purposes of Catabolic pathways
breakdown of larger molecules, release and storage of high energy molecules,
catabolic pathways are
oxidative, cofactors are reduced
Oxidative phosphorylation
1) oxidation of reduced cofactors and reduction of molecular oxygen
2) phosphorylation of ADP to ATP
how are the 2 processes of oxidative phosphorylation linked
proton gradient across mitochondrial membrane
overview of oxidative phosphorylation
reduced cofactors in glycolosis and CAC, ETC, proton gradient, ATP
where does this occur
mitochondrial membrane
Complexes 1-4 are
integral membrane proteins
coenzyme Q
lipid soluble coenzyme, hydrophobic, transports to Complex iii from i and ii, ubiquinol
cytochrome C
peripheral membrane protein
electrons move from ______ reduction potential
lower to higher
Flavin mononucleotide
FMN + 2H+ 2e- FMNH2
Iron-sulfur clusters
Fe3+ + e- Fe2+
Cytochrome heme group vs hemoglobin heme group
cytochrome prosthetic group does not have proximal histidine that prevents oxidation of Fe, cuz you want it to oxidize
higher reduction potential
more neg G
terminal electron acceptor
O2
what kind of transport uses redox reactions to transport protons across membrane
primary transport