Topic 7 Flashcards
metabolism
metabolites and metabolic intermediates go through a series of enzyme catalyzed reaction
2 main goals of metabolism
obtain usable chemical energy and make specific molecules
Anabolic pathways
use energy to make molecules (e- used to make new bonds), usually reductive
Catabolic pathways
release energy when bonds are broken (e- removed and bonds break), usually oxidative
Amphibolic pathways
both catabolic and anabolic depending on conditionns
food to metabolic intermediates is
catabolic
metabolic intermediates to cellular constituents is
anabolic
macromolecules that are not a significant food source
nucleic acids (nucleotides)
macromolecules that are ok food sources
protein
macromolecules that are great food sources
polysaccharides and tricylgycerols
carbohydrates are stored as ____ in ____ cells
glycogen in liver (hepatocytes) and muscle (myocytes) cells
hepatocytes
maintain blood glucose
myocytes
greedy, keeps fat for itself
fatty acids stored as
adipocytes
most significant fuel molecule
adipocytes
free energy change depends on
concentration of substances
Biochemical standard state
pH 7, [S] and [P] at 1M, 25 C temp, pressure 1 atm, [H2O] 55M
A reaction will only proceed if
G is neg
G > 0
NOT PROCEED
G < 0
SPONTANEOUS
G «_space;0
IRREVERSIBLE
G ~ 0
REVERSIBLE, EQUILIBRIUM
if reversible reaction, what can change direction
changes in concentration
even for a pathway to proceed
G < 0
