Topic 3 Flashcards
1
Q
Oligopeptides
A
large number of amino acids, synthetic residues
2
Q
Polypeptide
A
natural long chain of aa
3
Q
Protein
A
large polypeptide with biological function
4
Q
Primary Structure
A
- covalently bound amino acid sequence
- rigid/planar
- 3D structure determines function
5
Q
Folding conformations are limited….
A
to minimize steric conflicts
6
Q
Secondary Structure
A
- polypeptide backbone
- a-helix, B-sheet
7
Q
a-helix
A
H-bonds between backbone in the same helices
8
Q
B-sheets
A
H-bonds between neighbouring strands
9
Q
____ secondary structure linked by ____
A
regular, irregular
10
Q
Tertiary
A
All atoms in a polypeptide
- amino acid chains
- prosthetic groups
- arrangement of secondary structures
11
Q
Fibrous
A
- insoluble
- long filaments
- structural or connective
12
Q
Globular
A
- soluble
- non-polar core (hydrophobic side chains)
- polar surface (hydrophilic side chains)
13
Q
Regular found in ____ and ____ found outside
A
interior, irregular
14
Q
soluble globular protein’s driving force….
A
hydrophobic effect
15
Q
Salt bridges
A
- electrostatic interactions between - and +
- fine tune and stabilize 2 and 3 structures
