Topic 3: Protein Digestion Flashcards
How are proteins hydrolysed?
By a group of enzymes called peptidases
what group of enzymes hydrolyse proteins?
Peptidases
How many types of peptidases are there?
3
Name the 3 types of peptidases
Endopeptidase
Exopeptidases
Dipeptidases
What do endopeptidases do?
Hydrolyse peptide bonds inside a protein molecule and break it into peptide fragments
Name 2 endopeptidases
Pepsin
Trypsin
Where is pepsin produced?
The cells of the stomach lining
What is pepsin?
An endopeptidase in the stomach
What ph does pepsin work best at?
2
Which endopeptidase works best at ph 2?
Pepsin
What is trypsin?
An endopeptidase produced by the pancreas but released in small intestine
Where is trypsin produced?
In the pancreas
where is trypsin released?
Small intestine
What is the optimum ph of trypsin?
7 0r 8
Which endopeptidase works best at ph 7 or 8?
Trypsin
What does an Exopeptidase do?
Hydrolyse peptide bonds at the end of a protein molecule releasing a single amino acid or dipeptide
What is released after an Exopeptidase hydrolyses a protein?
A single amino acid or dipeptide
Where are Exopeptidases produced?
Epithelial cells
What does a Dipeptidase do?
They hydrolyse the peptide bond in a dipeptide and release 2 amino acids
What are Dipeptidases?
Exopeptidases that work on dipeptides
What is released after Dipeptidases hydrolyse proteins?
2 single amino acids
Where are Dipeptidases produced?
Epithelial cells
Dipeptidases are a type of what?
Exopeptidase
Why are Exopeptidase and dipeptidase could in epithelial cells that line the ileum and not different locations like endopeptidases?
They are membrane bound enzymes
