Topic 2-L2 - Prokaryotic Cell Morphology Flashcards
6 types of morphological
- coccus (cocci)
- Rod (rods)
- spirillum (spirilla)
- spirochete
- budding and appendaged
- filamentous
Cocci: spheres
Clusters = Staphylococci – Staphylococcus aureus
Common component of human microbiota (often nasal), opportunistic pathogen (often via wounds/cuts). Can enter bloodstream and cause life-threatening infections.
- Many S. aureus infections are by antibiotic-resistant strains (e.g.MRSA, VRSA) and are very difficult to treat clinically.
Cocci: spheres Pairs = diplococci – Neisseria gonorrhoeae
- Gram negative coccus
- Etiological agent of the common STD gonorrhea
Cocci: spheres Chains = streptococci – Streptococcuspyogenes
-The predominant “group A strep”
- Can cause a range of diseases, including “strep throat”. Can also
be carried by healthy individuals.
Bacilli: rods Salmonella enterica
- Common cause of “food poisoning” worldwide. Also cause of Typhoid Fever.
- Different S. enterica serovars – some rarely infect humans, some only infect humans.
Vibrio: comma shaped or bent rod Vibrio cholerae
- Important human pathogen, especially in developing world, that causes profuse diarrhea and dehydration.
Helical Helicobacter pylori
- Commonly found in human stomach, often innocuous
- Cause of vast majority of stomach ulcers, stomach cancers
Spirochetes Borrelia burgdorferi
- Pathogen that causes Lyme disease, transmitted by ticks
Appendaged/Budding Caulobactercrescentus
- Used as a model system to study bacterial cell cycle, asymmetric cell division
- Cell cycle can be synchronized, facilitating its characterization
Filamentous Chloroflexusaurantiacus
- Photosynthetic bacterium that does not produce O2
- Studied to understand the evolutionary origins of photosynthesis
Cell Shape can affect many aspects of day to day life
- Nutrient access/uptake (surface:volume ratio)
- Motility
- Attachment to surfaces
- Formation of biofilms
- Interactions with other microbes and/or eukaryotic host cells
Monomorphic:
one shape; observed in most pure cultures of bacteria
Pleomorphic:
multiple different morphologies for same bacterium
What causes different morphologies/changes of morphology?
- Differentiation into different cell types or spore formation
- Altered morphology in response to environmental cues
- Altered morphology due to mutation
Normally a bacillus (rod), becomes filamentous in a growth medium that induces
Mg2+ starvation