Topic 12 - Stress, Trauma and Psychopathology Flashcards
1
Q
What are some adverse effects of glucocorticoids in the hippocampus?
A
Disruption of LTP (long-term potentiation), neuron death, overt toxicity.
2
Q
What areas of the brain do ACEs affect?
A
Due to HPA axis dysregualtion:
1. nucleus accumbens
2. PFC
3. amygdala