Topic 11 Muscular system Flashcards
Describe the organization of the skeletal muscle from cell (skeletal muscle fibre) to whole muscle
First cells are called** fibres **
and the GROUP of fibres are called fascicles **
and the GROUP of fascicles are called whole muscle**
fibres
the cells of the skeletal muscle
Fascicles
groups of fibres
Whole muscle
groups of fascicles
Name the connective tissue layers that surround each skeletal muscle fibre, fascicle and whole muscle
Fascia = Connective tissue
- Epimysium (connective tissue) = surround entire muscle
- Perimysium (connective tissue) = surround dascicles
- Endomysium (connective tissue) = surround each muscle fibre
Epimysium
a type of connective tissue that surrounds entire muscle
Perimysium
a type of connective tissue that surrounds the fascicles
Endomysium
a type of connective tissue that surrounds each muscle fibre
Define tendon and aponeurosis
Well, the tendons and aponeuroses are extensions of the epi, peri and endomysium and they anchor muscles to bone (periosteum), cartilage, skin or fascia of other muscles
tendons = rope like e.g achilles
aponerosis = sheet like
describe the components within a skeletal muscle fibre
Large multinucleated cells
Parts of these cells :
1) sarcolemma = cell membrane
2) sarcoplasm = cytoplasm
3) myofibrils = intracellular strucutres (organelles)
- within each fibre there are several hundreds to thousands
- composed of sarcomeres (contractile units of muscle fibres)
4) T Tubules = continutations of sarcolemma that extend deep into fibre (cell)
- directly encircle myofilaments of myofibrils at junction A and I bands (2/sarcomere)
5) Sarcoplasmic reticulum = smooth ER
- forms a triad = 2 enlarged areas of SE (terminal cisternae) and T - tubule
Sarcolemma
Cell membrane of the large multinucleated cells of the skeletal muscle fibre
Sarcoplasm
Cytoplasm of the large multinucleated cells or skeletal muscle fibre
Myofibrils
Part of the large multinucleated cells of skeletal muscle fibre
- intracellular structures (organelles)
- within each fibre contains several hundreds - thousands
- composed of sarcomeres
define sarcomere
composed of proteins
describe the arrangement and composition of the following components of a sarcomere
Sarcomeres are made up of proteins and they contains 2 types of myofilaments (which are proteins)
1) thin filaments
- made of actin (functions in contraction)
- tropomyosim and troponin (help regulate contraction (regulatory proteins)
2) thick filaments
- composed of myosin (functions in contraction)
- attached to z discs by titin
- has rod-like tail with 2 gobular heads (heads extend toward actin and attaches to it - forming a cross bridge)
-
the myofilaments creat dark and light bands (striations) of the sarcomere
Banding pattern:
1) A band
2) H zone
3) I band
4) Z discs
5) M line
- sarcomeres join end to end (at Z discs) to form myofibrils