Topic 11 Final Exam

Question 1

1. Where does paresis occur due to lesions in the Primary Motor Cortex?

Answer 1

Primary motor cortex paresis in that body area would cause that area to experience weaknesses

Question 2

1. Where does paresis occur due to lesions in the Premotor Cortex?

Answer 2

In premotor proximal muscles, like the trunk would be affected (hard time rotating) won’t be fingers or arms only one’s close to the heart

Question 3

2. What does over activity in the Subthalamic Nucleus (STN) and Globus Pallidus internus (GPi) &
   Substantia Nigra par reticulata (SNr) do to the excitatory input to the cortex?

Answer 3

Decreased excitation

Question 4

3. How does deep brain stimulation (DBS) alleviate the symptoms of Parkinson’s Disease?

Answer 4

Silencing and reducing the amount of firing/shaking in the hands and body

Question 5

4. What is the difference between Open- and Closed-Loop DBS with respect to the control of the
   stimulation?

Answer 5

Open look - Stimulator either on or off and programming Session and thats it

Closed loop - Stimulator - Sensor - Processing Unit - Programmer - back to stimulator

Will turn off and on when in normal or adbormal state

Only stimulating when brain is in abnormal state