Exam 1 Flashcards
What is the Sodium-Potassium pump? What does it do, how, and why?
maintains the membrane potential
The specific function of the sodium potassium pump is to move potassium ions into the cell and sodium ions out of the cell to drive an action potential. This creates a fluctuating concentration inside and outside of the cell causing the cell to pump more sodium and potassium in and out of the cell, resulting in depolarization and repolarization.
What are the steps in generation of Action Potential?
a. Draw and label the phases
b. Describe what is occurring during each phase
i. What channels are opening/closing
ii. How are ions moving (in/out)
LOOK AT STUDY GUIDE
What are the two types of post-synaptic potentials (PSP)?
Excitatory and Inhibitory post synaptic potential
What is spatial summation of PSP’s?
Example: ?????
Two different nuerons simultaneous stimuli at different location cause PSP that add together.
Spatial Summation PSPs?
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When would an action potential be generated?
When they fire and add together to reach threshold
Spatial Summation of PSP’s
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Describe an example when an action potential would not be generated?
Change in membrane potential can cancel each other out
What is Temporal Summation of PSP’s?
Same cell Two excitatory stimuli close in time cause EPSP’s that add together
Temporal Summation of PSP’s?
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Describe an example when an action potential would be generated?
Fire close to the same time from one cell to reach threshold
Temporal Summation of PSP’s?
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Describe an example when an action potential would NOT be generated?
Doesn’t fire close close therefore it wont reach threshold
Draw parts of the neuron: Soma, Dendrites, Axon, Hillock, Axon Collateral, Synapse
Three general types of neurons and what they do
Afferent: Sensory - dorsal root - sends signal to peripheral to cns
Efferent: Motor - Ventral root - sends signal from cns to pns
Interneuron: In CNS between afferent + efferent
Why is it good to have an axon with a large diameter?
It decreases resistance, therefore signal will travel down faster
Why is it bad to have an axon with a large diameter?
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Takes more myelination and more energy
Has a higher chance of a leakier membrane
What does myelination do?
It allows the charge to maintain longer and allows the signal to travel faster down the axon
Describe and compare saltatory conduction and continuous conduction along an axon?
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Saltatory conduction: Occurs in myelinated axons aka faster (jumps from node of ranvier) (voltage gated channels only at these nodes)
Continuous conduction: Unmyelinated axons aka slower (travels down the entire length of axon) (voltage gated channels Na found along the whole axon)
What cells are responsible for myenlination of neurons in the CNS and PNS?
Schwann cell for PNS
Oligodendrocytes for CNS
How does a chemical synapse work? Describe the steps for signal transmission.
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Picture
How does an electrical synapse work?
Gap junctions which allows ion to move in both directions (bidirectional)
Has a passive current flow and is extremely fast