Topic 10.2 - Inheritance Flashcards
Segregation
Separation of the two alleles of a gene
Not always independent - linked genes will not segregate independently unless very far away on the chromosome.
Linked genes
Gene loci are said to be linked if on the same chromosome.
Autosomal linkage - genes that are linked on an autosomal gene
Allosomal (sex) linkage - genes that are linked on an allosomal (sex) gene
Dihybrid crossing
(page 446 biobook)
Only works for unlinked genes
Continuous variation
Polygenic traits show continuous variation. These additive genes impact each other to affect the phenotype
Shows a normal distribution
(? check below ?)
More unlinked genes with more co-dominant alleles, a wider normal distribution - more phenotypic variants.
Less unlinked genes with less co-dominant alleles, leads to a narrower normal distribution.
Exceptions to Mendel’s rule of hybrid crossing
1) Linked genes (alleles may not separate independently)
2) Sex Linkage (X chromosome gene may cause only one allele - ie for males. ie haemophilia, colourblindness)
3) Mutations
Recombinant
Different allele combinations to both parents.
Environmental influence
Skin colour due to polygenic inheritance, but also to the sun.
Chi-squared tests
(page 453 - 454 biobook)
Mrs Gradley’s topic 10.2 powerpoints
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Table of exp freq vs observed (exp is found by doing expected ratio x total amount)
Equation is sigma (observed - exp)/exp
If found value is < given value at a certain signif level, accept Ho and there is no evidence that traits are linked