Topic 10 - Papillomatoses. Flashcards
Which family does papillomatises belong to?
Papillomaviridae Family
How many subfamilies does Papillomaviridae Family have? Name them
2
Firstpapillomavirinae
Secondpapillmavirinae
Which species is affected by Secondpapillmavirinae?
Fish
Which species is affected by Firstpapillomavirinae?
human and cattle
Name important features of the Papillomaviridae Family:
- Icosahedral shape
- Non-enveloped and Very strong resistance
- Stenoxen
- Oncogen
- Latent
Replication of Papillomaviridae Family:
Via viral transcriptase
there is no replication in tissue culture and keratin is needed!!
How many types of papillomatosis viruses do we have?
6
How many types of papillomatosis viruses infects horses and which of them?
2
1 and 2
Where can we find type 1,2 and 3?
in the skin, all over the body
Where can we find type 4?
Intestines
Where can we find type 5 and 6?
Skin of udder
What is the route of infection in case of papillomatosis?
Skin and mucoisa through an opening such as trauma or a vector
Incubation time of papillomatosis:
1-2 months in every specie
Which site can we find the repicaiton and shedding?
Stratum corneum
Name different “diseases” caused by papillomavirus
- Bovine papillomatosis
- Horse papillomatosis
- Horse sarcoid
- Dog/cat papillomatosis
Common areas affected by bovine papillomatosis:
near the eye, horn base, abdomen, neck, dug, withers
Rare areas affected by bovine papillomatosis:
oral cavity, pharynx, oesophagus, vagina/penis
Is bovine papillomatosis benign or malignant?
benign, can heal by itself
clinical signs of bovine papillomatosis:
Millet-size, greyish, stuffed, non-painful nodules
Diagnostical methods of bovine papillomatosis:
either virus detection or antibodies detection
Virus detection: PCR, DNA hybridsation, in situ, histopathology
Antibodies detection: spontaneous healing
Treatment of bovine papillomatosis:
- Surgical removal
- Vaccine
Causative agent of horse papillomatosis:
Equine papillomatosis, 2 types
Common areas of infection in case of horse papillomatosis:
head and neck (blowhole, jaw)
Rare areas of infection in case of horse papillomatosis:
ears, hoof, palpebra, genitalia
Age of horses affected by horse papillomatosis:
under 3 years
Causative agent of horse sarcoid:
Bovine papillomatosis virus 1 and 2
Common areas of infection in case of horse sarcoid:
Head, abdomen, hoof
Is horse sarcoid benign or malignant?
Benign, but it is agressive
Age of infected animals in dog/cat papillomatosis:
Puppy/kitty or young
Area infection in dog/cat papillomatosis:
Oral cavity, genitalia
Can Dog/Cat Papillomatosis be healed?
Yes, by spontaneous healing after 2-6 months
