Top1-Ch1-ThingsMissed Flashcards
What is Biochemistry
is the study of the chemical processes in living organisms. It deals with the structure and function of cellular components such as proteins, carbohydrates, lipids, nucleic acids and other biomolecules.’
What are the limits to cell size?
Upper limit of cell set by rate of diffusion- ratio surface area to volume
Hence if cell size is too large, it will not have enough surface area to diffuse substances (eg. O2) into all parts of it
A is r2 while volume is r3
Prokaryotic V Eukaryotic
Prokaryotic:
- Small (generally 1-10 µm)
- Single cell organism (usually)
- Nucleoid- no membrane, cytoplasmic DNA
- Low DNA content
- Cytoplasmic DNA plasmids
- No membrane bound organelles
Eukaryotic:
- Larger (generally 5-100 µm)
- Single or multicellular organism
- Nucleus with nuclear envelope, DNA condensed into nucleus
- High DNA content
- No cytoplasmic DNA plasmids
- Organelles: eg. Golgi, ER, mitochondria, peroxisomes
Animal cell picture from slides
Macromolecules are held together by covalent or non-covalent bonds? Name the bonds.
non-covalent bonds
- Hydrogen bonds – between polar groups
- Ionic interactions – between charged groups
- Hydrophobic interactions (non-polar groups in aqueous solution)
- Van der Waals interactions (very close proximity, ≈ “exact fit”)
Name four classes of macromolecules
- Proteins - amino acids
- Lipids - fatty acids, glycerol
- Polysaccharides (carbohydrates) - sugars
- Nucleic acids (DNA, RNA) - nucleotides
In general, polymers are large molecules formed by stringing together smaller compounds or monomers.