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NAPLEX > Top Drugs > Flashcards

Top Drugs Flashcards

1
Q

Acyclovir

A

Zovirax, Sitavig

Viral infections

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2
Q

Adalimumab

A 
Humira
anti-TNF
RA, ank spond, psoriasis, IBD, autoimmune
do not give live vaccines, do not shake
activation of malignancies, infections
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3
Q

Albuterol (inhalation)

A

Proventil HFA, ProAir HFA, Ventolin HFA
SABA
asthma, Bronchospasm

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4
Q

Albuterol/Ipratropium

A

Combivent Respimat
SABA/SAMA
Bronchospasm, COPD

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5
Q

Alendronate

A 
Binosto, Fosamax
bisphosphonate
Osteoporosis
s/e: hypocalcemia
sit/stand 30 min after taking, take in morning w/ full glass water, take Ca and Vit D
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6
Q

Allopurinol

A 
Aloprim, Lopurin, Zyloprim
Gout
s/e: gout, rash, nausea
use w/ colchicine for 1st 3-6 months
do not use with azathioprine or mercaptopurine
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7
Q

Alprazolam

A

Xanax

Anxiety, panic disorder

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8
Q

Amitriptyline

A

Elavil
TCA
Depression, pain adjuvant
s/e: orthostasis, cardiotoxicity, QT prolongation
do not use w/ MAOi (phenelzine, tranylcypromine, isocarboxazid)

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9
Q

Amlodipine

A

Norvasc
DHP CCB - peripheral artery vasodilation
Angina, HTN
s/e: reflex tachycardia, peripheral edema

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10
Q

Amoxicillin

A

Amoxil, Moxatag

Bacterial infections

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11
Q

Amoxicillin/clavulanate

A

Augmentin

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12
Q

Mixed amphetamine salts

A

Adderall

ADHD

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13
Q

Aripiprazole

A

Abilify
2nd gen antipsychotic
Schizophrenia, bipolar, MDD, treatment-resistant depression

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14
Q

Atenolol

A

Tenormin
Beta Blocker - b1 selective
HTN
s/e: masks hypoglycemia, fatigue, dizzy

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15
Q

Atomoxetine

A

Strattera
ADHD
non-stimulant

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16
Q

Atorvastatin

A

Lipitor

HLD

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17
Q

Azithromycin

A

Zithromax, Z-pak
macrolide
atypical coverage, CAP
s/e: QT prolongation, hepatotoxicity, GI upset

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18
Q

Beclomethasone (inhalation)

A

Qvar
Inhaled corticosteroid
Asthma
s/e: oral candidiasis - rinse mouth, dysphonia

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19
Q

Benazepril

A

Lotensin
ACEi - decrease vasoconstricition, decrease aldosterone secretion
HTN
s/e: cough, angioedema, hyperkalemia, inc SCr

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20
Q

Bimatopost (ophthalmic)

A

Lumigan
prostaglabin analog - moves fluid out of eye to dec IOP
glaucoma
s/e: darkening of iris/eyelashes eyelash growth/thickening

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21
Q

Brimonidine (ophthalmic)

A

Alpha fan P, alphagon
alpha-2 inhibitor
Open-angle glaucoma

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22
Q

Budesonide

A

Entocort EC, Uceris - Chron’s, Colitis
Pulmicort - ICS for asthma
s/e: oral candidiasis - rinse mouth, dysphonia

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23
Q

Budesonide/formoterol (inhalation)

A

Symbicort
ICS/LABA
Asthma, COPD

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24
Q

Buprenorphine/naloxone

A

Suboxone

Opioid dependence

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25
Q

Bupropion

A 
Wellbutrin, Zyban
dopamine + norepi reuptake inhibitor
Depression, smoking cessation
s/e: dry mouth, insomnia, weight loss, seizures
c/i w/ seizures
take in the morning
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26
Q

Buspirone

A

Buspar

Anxiety

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27
Q

Carisoprodol

A

Soma

Muscle relaxer, pain adjuvant

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28
Q

Carvedilol

A

Coreg
non-selective Beta Blocker and Alpha-1 blocker
HTN, HF
s/e: hyperglycemia

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29
Q

Celecoxib

A 
Celebrex
COX2 selective NSAID
OA, RA, acute pain
c/i: sulfa allergy, pregnancy
inc MI/stroke risk
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30
Q

Cephalexin

A

Keflex

Bacterial infections

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31
Q

Cetirizine

A

Zyrtec
antihistamine
Allergic rhinitis

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32
Q

Ciprofloxacin

A

Cipro
quinolone
Bacterial infections
covers pseudomonas
s/e: tendon rupture, peripheral neuropathy, QT prolongation, photosensitivity, hepatotoxicity
do not use in children, separate from cations

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33
Q

Citalopram

A

Celexa
SSRI
Depression
do not use w/ MAOi (phenelzine, tranylcypromine, isocarboxazid)

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34
Q

Clindamycin

A

Cleocin
Bacterial infections
s/e: C/ diff colitis
perform induction test

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35
Q

Clonidine

A 
Catapres, Kapvay
Alpha-2 agonist - decrease BP by decreased norepi release = decreased SVR, decreased HR
HTN, ADHD
s/e: dry mouth, somnolence, hypotension
do not stop suddenly
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36
Q

Clopidogrel

A

Plavix
Antiplatelet
ACS, reduce stroke/MI risk

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37
Q

Colchicine

A

Colcrys, Mitigare

Gout

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38
Q

Cyclobenzaprine

A

Amrix, Flexeril

Muscle relaxer

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39
Q

Dabigatran

A 
Pradaxa 
Direct thrombin inhibitor
Anticoagulant
c/i prosthetic heart valve
reversal: idarucizumab (Praxbind)
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40
Q

desvenlafaxine

A

Pristiq
SNRI
depression
do not use w/ MAOi (phenelzine, tranylcypromine, isocarboxazid)

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41
Q

dexmethylphenidate

A

Focalin

ADHD

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42
Q

diazepam

A

Valium

anxiety, alcohol withdrawal, seizures

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43
Q

diclofenac

A 
Voltaren, Cambia
COX2 selective NSAID
OA, RA, pain
avoid in women of childbearing potential
inc MI/stroke risk
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44
Q

digoxin

A

Lanoxin, Digitek, Digox
inhibits Na/K/ATPase pump
pos. inotrope (inc contractility), neg chronotrope (slows HR) - improves exercise tolerance, QOL
HF, a-fib

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45
Q

diltiazem

A

Cardizem, Cartia, Tiazac
non-DHP CCB - control arrythmias, neg inotrope, neg chronotrope
HTN, angina
s/e: edema, gingival hyperplasia

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46
Q

divalproex

A

Depakote

seizures, bipolar, migraine prophy

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47
Q

donepezil

A

Aricept
scetylcholinesterase inhibitor = inc ACh
alzheimer’s disease
s/e: nausea, insomnia - give at night for less nausea, give in morning for less insomnia

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48
Q

dorzolamide/timolol (ophthalmic)

A

Cosopt
carbonic anhydrase inhibitor / beta blocker
glaucoma
s/e: burning, stinging, change in vision, dry eye

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49
Q

doxazosin

A

Cardura
Alpha-1 blocker - vasodilation of arteries and veins
HTN, BPH
not recommended by JNC8
reduces bladder obstruction, improving urine flow
s/e: orthostatic hypotension, syncope, abnormal ejaculation, floppy iris syndrome w/ cataracts

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50
Q

doxycycline

A

Vibramycin, Doxy
tetracycline
CA-MRSA skin infections, VRE, UTIs
s/e: teeth discoloration, less bone growth, photosensitivity, SJS/TEN
do not use in children <8, pregnancy, breastfeeding
separate from divalent cations

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51
Q

duloxetine

A

Cymbalta
SNRI
anxiety, depression, chronic pain
do not use w/ MAOi (phenelzine, tranylcypromine, isocarboxazid)

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52
Q

dutasteride

A

Avodart
5-alpha reductase inhibitor
BPH - use only if enlarged prostate
reduces prostate size, decreases PSA levels
s/e: impotence, dec libido, abnormal ejaculation
c/i in pregnancy, women of childbearing age

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53
Q

enalapril

A

Vasotec, Epaned
ACEi - decrease vasoconstricition, decrease aldosterone secretion
HTN, HF
s/e: cough, angioedema, hyperkalemia, inc SCr

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54
Q

enoxaparin

A 
Lovenox
LMWH
anticoagulant
do not use w/ history of HIT
s/e: inc LFTs, thrombocytopenia
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55
Q

ergocalciferol

A

Drisdol

Vit. D deficiency

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56
Q

escitalopram

A

Lexapro
SSRI
depression, anxiety
do not use w/ MAOi (phenelzine, tranylcypromine, isocarboxazid)

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57
Q

esomeprazole

A

Nexium
PPI
GERD, Peptic ulcers
s/e: osteoporosis, fractures, C. diff, hypomagnesemia

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58
Q

estradiol

A

Estrogel, Evamist, Femring, Minvelle

estrogen replacement

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59
Q

conjugated estrogens

A

Prempro, Premarin

estrogen replacement

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60
Q

eszopiclone

A

Lunesta
act on benzo receptors to inc GABA
insomnia
s/e: somnolence, ataxia, parasomnias (unusual actions while sleeping)

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61
Q

etanercept

A 
Enbrel
anti-TNF
RA/OA, plaque psoriasis
weekly injection, do not give live vaccines, do not shake
activation of malignancies, infections
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62
Q

exenatide

A

Byetta, Bydureon
GLP-1 agonist - inc insulin secretion, dec glucagon secretion, slows gastric emptying
T2DM
s/e: weight loss

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63
Q

Ezetimibe

A

Zetia
inhibits cholesterol absorption
high cholesterol

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64
Q

ezetimibe/simvastatin

A

Vytorin

hyperlipidemia

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65
Q

famotidine

A

Pepcid
H2RA
GERD, peptic ulcers
s/e: confusion

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66
Q

fenofibrate

A

Lipofen

Hyperlipidemia

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67
Q

fentanyl

A

Actiq, Duragesic
Pain
1 patch Q72h

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68
Q

finasteride

A

Proscar, Propecia
5-alpha reductase inhibitor
BPH, male hairloss
use only if enlarged prostate - reduces prostate size and PSA levels
s/e: impotence, dec libido, abnormal ejaculation
c/i in pregnancy, women of childbearing age, women shouldn’t handle

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69
Q

fluoxetine

A

Prozac, Sarafem
SSRI
depression, OCD, panic disorder, PMDD
do not use w/ MAOi (phenelzine, tranylcypromine, isocarboxazid)

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70
Q

fluticasone (inhalation)

A

Flovent HFA, Flovent diskus
ICS
asthma
s/e: oral candidiasis - rinse mouth, dysphonia

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71
Q

fluticasone (nasal)

A

Flonase

Rhinitis

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72
Q

fluticasone/salmeterol

A

Advair diskus, Advair HFA
ICS/LABA
asthma, COPD

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73
Q

furosemide

A

Lasix

edema, HTN

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74
Q

gabapentin

A

Neurontin, Gralise

seizures, postherpetic neuralgia

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75
Q

glimepiride

A 
Amaryl
sulfonylurea
T2DM - inc insulin levels
s/e: weight gain
take w/ breakfast
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76
Q

glipizide

A 
Glucotrol
sulfonylurea - inc insulin levels
T2DM
s/e: weight gain
take w/ breakfast
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77
Q

guaifenesin

A

Mucinex

expectorant

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78
Q

hydralazine

A

Apresoline
direct vasodilator of arteries
HTN
s/e: hypotension, reflex tachycardia, palpitations

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79
Q

hydrochlorothiazide

A

Microzide

edema, HTN

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80
Q

HCTZ/triamterene

A

Dyazide

edema, HTN

81
Q

HCTZ/valsartan

A

Diovan HCT
thiazide/ARB
HTN
s/e: hypotension, angioedema, dizziness

82
Q

hydrocodone/acetaminophen

A

Norco, Vicodin, Lortab

pain

83
Q

hydroxyzine

A

Vistaril

axiety, sedation

84
Q

ibandronate

A 
Boniva
bisphosphonate
osteoporosis
s/e: hypocalcemia
sit/stand 30 min after taking, take in morning w/ full glass water, take Ca and Vit D
85
Q

ibuprofen

A

Advil, Motrin

pain, fever, arthritis

86
Q

irbesartan

A

Avapro
ARB - inhibits renin-angiotension system
HTN, diabetic neuropathy
s/e: angioedema, hypotension, dizzy, cough

87
Q

isosorbide mononitrate

A

Imdur, Monoket

angina

88
Q

lamotrigine

A

Lamictal
anti-epileptic
seizures, bipolar
s/e: irritability, weakness, dizziness

89
Q

lansoprazole

A

Prevacid
PPI
GERD, ulcers
s/e: osteoporosis, fractures, C. diff, hypomagnesemia

90
Q

latanoprost (ophthalmic)

A

Xalatan
prostaglabin analog - moves fluid out of eye to dec IOP
glaucoma
s/e: darkening of iris/eyelashes eyelash growth/thickening

91
Q

levalbuterol (inhalation)

A

Xopenex
SABA
asthma, bronchospasm

92
Q

levetiracetam

A

Keppra
anti-epileptic
seizures
s/e: irritability, weakness, dizziness

93
Q

levofloxacin

A

Levaquin
quinolone
bacterial infections
respiratory quinolone - covers S. pneumo
s/e: tendon rupture, peripheral neuropathy, seizures, QT prolongation, photosensitivity, hepatotoxicity
do not use in children, separate from cations

94
Q

levothyroxine

A

Synthroid, Unithroid

hypothyroidism

95
Q

liraglutide

A

Victoza, Saxenda
GLP-1 agonist - inc insulin secretion, dec glucagon secretion, slows gastric emptying
T2DM
s/e: weight loss

96
Q

lisdexamphetamine

A

Vyvanse

ADHD

97
Q

lisinopril

A

Zestril, Prinivil
ACEi - decrease vasoconstricition, decrease aldosterone secretion
HTN, HF
s/e: cough, angioedema, hyperkalemia, inc SCr

98
Q

lisinopril/HCTZ

A

Zestoretic
ACEi / thiazide
HTN
s/e: cough, angioedema, hyperkalemia, inc SCr

99
Q

lorazepam

A

Ativan
benzodiazepine
Anxiety, insomnia
do not use if 65+ (Beer’s list)

100
Q

losartan

A

Cozaar
ARB - inhibits renin-angiotensin system
HTN, HF, diabetic nephropathy
s/e: angioedema, hypotension, dizzy, cough

101
Q

losartan/HCTZ

A

Hyzaar
ARB/thiazide
HTN
s/e: angioedema, hypotension, dizzy, cough

102
Q

lovastatin

A

Altoprev, Mevacor

high cholesterol

103
Q

meloxicam

A

Mobic
COX2 selective NSAID
OA/RA
inc MI/stroke risk

104
Q

memantine

A

Namenda
inhibits glutamate binding to NMDA receptors
Alzheimer’s disease

105
Q

mesalamine

A

Apriso, Canasa, Delzicol

IBD

106
Q

metformin

A 
Glucophage, Fortamet
biguanide - dec. glucose output, inc insulin sensitivity
T2DM
do not use if GFR <30
s/e: lactic acidosis, NVD
107
Q

methocarbamol

A

Robaxin

muscle relaxer, pain adjuvant

108
Q

methotrexate

A 
Otrexup, Rasuvo, Xatmep
DMARD
cancer, RA, psoriasis
c/i in pregnancy, do not use w/ alcohol
s/e: alopecia, photosensitivity
folate decreases s/e
109
Q

methylphenidate

A

Concerta, Ritalin, Metadate

ADHD, narcolepsy

110
Q

methylprednisolone

A

Medrol, methapred

corticosteroid

111
Q

metoprolol

A 
succinate = Toprol XL
tartrate = Lopressor
Beta Blocker - b1 selective
HTN, angina, migraine prophy
s/e: masks hypoglycemia, fatigue, dizzy
112
Q

metronidazole

A

Flagyl
antibiotic - anaerobes, protozoa, vaginosis, C. diff
s/e: metallic taste; avoid alcohol
don’t use during 1st trimester pregnancy

113
Q

mirtazapine

A

Remeron
depression
s/e: weight gain

114
Q

modafinil

A

Provigil

narcolepsy

115
Q

mometasone (inhalation)

A

Asmanex, Twisthaler

asthma

116
Q

mometasone (nasal)

A

Nasonex

allergic rhinitis

117
Q

montelukast

A 
Singulair
leukotriene receptor antagonist (LTRA)
asthma, allergies
take in evening
s/e: headache
can sprinkle on food - take w/in 15 minutes
118
Q

morphine

A

Kadian, MS Contin

pain

119
Q

moxifloxacin

A

Avelox
quinolone
bacterial infections
respiratory quinolone - covers S. pneumo
s/e: tendon rupture, peripheral neuropathy, seizures, QT prolongation, photosensitivity, hepatotoxicity
do not use in children, separate from cations

120
Q

mupirocin (topical)

A

Bactroban, Centany

nasal treatment to eliminate MRSA colonization

121
Q

naproxen

A

Naprosyn, Anaprox, Aleve, Naprosyn
NSAID
RA, OA

122
Q

nebivolol

A

Bystolic

HTN

123
Q

nifedipine

A

Adalat, Afeditab, Procardia
DHP CCB - peripheral artery vasodilation
HTN, Reynaud’s syndome
s/e: reflex tachycardia, peripheral edema

124
Q

nitroglycerin (sublingual)

A

Nitrostat
angina
keep in original glass, amber vial
do not use with PDE-5 inhibitors (Cialis, Viagra)

125
Q

olanzapine

A

Zyprexa

schizophrenia, bipolar

126
Q

olmesartan

A

Benicar
ARB - inhibits renin-angiotensin system
HTN
s/e: angioedema, hypotension, dizzy, cough

127
Q

olopatadine (ophthalmic)

A

Pataday, patanol
antihistamine
allergic conjunctivitis

128
Q

omega-3

A

Lovaza, Omacor
hypertriglyceridemia
s/e: increased LDL

129
Q

omeprazole

A

Prilosec
PPI
GERD, ulcers
s/e: osteoporosis, fractures, C. diff, hypomagnesemia

130
Q

ondansetron

A

Zofran
5HT3 antagonist
nausea/vomitting, CINV
acute CINV w/in 24 hrs of chemo

131
Q

oxcarbazepine

A

Trleptal, Oxtellar

seizures

132
Q

oxybutinin

A

Ditropan
anticholinergic
overactive bladder
s/e: dizziness, drowsiness, dry mouth

133
Q

oxycodone

A

OxyContin, Roxicodone, Oxaydo

prain

134
Q

oxycodone/acetaminophen

A

Percocet, Roxicet, Endocet

pain

135
Q

pantroprazole

A

Protonix
PPIs
GERD, ulcers
s/e: osteoporosis, fractures, C. diff, hypomagnesemia

136
Q

paroxetine

A

Paxil
SSRI
depression, anxiety
do not use w/ MAOi (phenelzine, tranylcypromine, isocarboxazid)

137
Q

phentermine

A

Adipex-P, Qsymia, Lomaira

weight loss

138
Q

pioglitazone

A 
Actos
TZD - inc insulin sensitivity
T2DM
s/e: peripheral edema, weight gain
c/i in HF
139
Q

potassium chloride

A

Klor-Con

potassium replacement

140
Q

pravastatin

A

Pravachol

high cholesterol

141
Q

prednisone

A

Rayos

corticosteroid

142
Q

pregabalin

A

Lyrica

neuropathic pain, seizures, fibromyalgia

143
Q

promethazine

A 
Phenergan
dopamine agonist
anti-emetic, antihistamine
CINV, motion sickness
s/e: QT prolongation, arrythmias, sedation, EPS, seizures
do NOT use in children
144
Q

propranolol

A

Inderal, Innopran
non-selective Beta Blocker - b1 and b2
HTN, migraine prophylaxis
s/e: hyperglycemia

145
Q

quetiapine

A

Seroquel
2nd gen antipsychotic
schizophrenia, bipolar, treatment-resistant depression

146
Q

quinapril

A

Accupril
ACEi - decrease vasoconstricition, decrease aldosterone secretion
HTN
s/e: cough, angioedema, hyperkalemia, inc SCr

147
Q

ramipril

A

Altace
ACEi - decrease vasoconstricition, decrease aldosterone secretion
HTN, HF
s/e: cough, angioedema, hyperkalemia, inc SCr

148
Q

ranitidine

A

Zantac
H2RA
GERD, ulcer
s/e: confusion

149
Q

ranolazine

A

Ranexa

angina

150
Q

risperidone

A

Risperdal
2nd gen antipsychotic
Schizophrenia, bipolar

151
Q

rituximab

A

Rituxan
non-TNF biologic - depletes CD20 B cells
RA, CLL, NHL
pre-medicate w/ steroid, APAP, antihistamine
do not give w/ other biologics or live vaccines

152
Q

rivaroxaban

A

Xarelto
Xa inhibitor
anti-coagulant
take w/ food

153
Q

rivastigmine

A

Exelon

Alzheimer’s, Parkinson’s

154
Q

rizatriptan

A

Maxalt

migraine

155
Q

ropinirole

A

Requip
dopamine agonist
Parkinson’s, RLS

156
Q

rosuvastatin

A

Crestor

high cholesterol

157
Q

saxagliptin

A

Onglyza
DPP-4 inhibitor - dec glucagon secretion, dec glucose, inc insulin release
T2DM
s/e: pancreatitis, risk of HF

158
Q

sertraline

A

Zoloft
SSRI
depression, anxiety
do not use w/ MAOi (phenelzine, tranylcypromine, isocarboxazid)
antidepressant of choice if cardiac issues

159
Q

sildenafil

A 
Viagra, Ravatio
PDE-5 inhibitors
ED, PAH
s/e: hypotension
do not use with nitates
160
Q

simvastatin

A

Zocor

HLD

161
Q

sitagliptin

A

Januvia
DPP-4 inhibitor - dec glucagon secretion, dec glucose, inc insulin release
T2DM
s/e: pancreatitis, risk of HF

162
Q

sitagliptin/metformin

A

Janumet

T2DM

163
Q

solifenacin

A

Vesicare
anticholinergic
overactive bladder
s/e: dizziness, drowsiness, dry mouth

164
Q

spironolactone

A

Aldactone
K-sparing diuretic
edema, CHF, HTN, hypokalemia tx
S/e: gynecomastia, breast pain, hyperkalemia

165
Q

sulfamethoxazole/trimethoprim

A 
Bactrim, Septra
sulfonamide abx
MRSA, UTI, E. coli, H. flu, PCP prophy
s/e: SJS/TEN, crystalluria, photosensitivity, Coombs test, hyperkalemia
increases INR, monitor w/ warfarin
166
Q

tadalafil

A 
Cialis, Adcirca
PDE-5 inhibitor
ED, PAH
s/e: hypotension, impaired color vision, hearing loss, vision loss
do not use with nitrates
167
Q

tamsulosin

A

Flomax
selective alpha-1a blocker
BPH
reduces bladder obstruction, improves urine flow
s/e: floppy iris syndrome w/ cataracts, abnormal ejaculation, orthostasis
give at bedtime to reduce orthostasis

168
Q

temazepam

A

Restoril
insomnia
do not use if 65+ (Beer’s list)

169
Q

testosterone

A

Androderm, Androgel, Axiron, Fortesta
testosterone replacement
s/e: clot risk, inc prostate growth, inc HCT, BPH, balding, gynecomastia
CV risk if used w/o low T
topical gel used in mornings, patch at night

170
Q

tiotropium

A

Spiriva
LAMA
asthma, COPD

171
Q

tizanidine

A

Zanaflex
antispasmodic
muscle spasm, pain adjuvant
s/e: hypotension, dry mouth, weakness

172
Q

tolterodine

A

Detrol
anticholinergic
overactive bladder
s/e: dizziness, drowsiness, dry mouth

173
Q

topiramate

A

Topamax
seizures, migraine prophy
s/e: weight loss, fetal toxicity

174
Q

tramadol

A

Ultram
pain
do not use in children <12
caution: seizures, serotonin syndrome, breastfeeding
can cause serotonin syndrome w/ SSRIs, etc.

175
Q

trazodone

A

Desyrel, Oleptro
depression
s/e: sedation, priapism

176
Q

triamcinolone

A

Kenalog, Triescence

corticosteroid

177
Q

valacyclovir

A

Valtrex

antiviral

178
Q

valsartan

A

Diovan
ARB - inhibits renin-angiotensin system
HTN, HF
s/e: angioedema, hypotension, dizzy, cough

179
Q

venlafaxine

A

Effexor
SNRI
depression, anxiety
do not use w/ MAOi (phenelzine, tranylcypromine, isocarboxazid)

180
Q

verapamil

A

Calan, Verelan
non-DHP CCB - control arrythmias, neg inotrope, neg chronotrope
angina, HTN, arrhythmia
s/e: edema, gingival hyperplasia

181
Q

warfarin

A

Coumadin, Jantoven

anti-coagulant

182
Q

Zolpidem

A

Ambien, Edular, Intermezzo
act on benzo receptors to inc GABA
insomnia
s/e: somnolence, ataxia, parasomnias (unusual actions while sleeping)

183
Q

flumazenil

A

benzodiazepine reversal/antidote

184
Q

fexofenadine

A

Allegra
antihistamine
allergic rhinitis

185
Q

hydroxychloroquine

A 
Plaquinil
DMARD
RA,OA
s/e: vision changes/loss, pigmentation changes
monitor w/ eye exam
186
Q

idarcizumab

A

Praxbind

dabigatran (Pradaxa) reversal

187
Q

amiodarone

A

Pacerone, Nexterone
antiarrhythmic - class 3 (blocks K channels)
DoC if HF + arrhythmia
s/e: pulmonary toxicity, thyroid issues, optic neuropathy, photosensitivity
decrease Digoxin dose by 50%, warfarin by 30-50%
avoid grapefruit

188
Q

oxymetazoline

A

Afrin
intranasal decongestant
allergic rhinitis
use <3 days, or rebound congestion

189
Q

canagliflozin

A 
Invokana
SGLT2 - inc glucose excretion
T2DM
s/e: yeast/genital infections, pyelonephritis, AKI, ketoacidosis, weight loss
risk of foot/leg amputations
c/i GFR <30
190
Q

dapagliflozin

A 
Farxiga
SGLT2 - inc glucose excretion
T2DM
s/e: yeast/genital infections, pyelonephritis, AKI, ketoacidosis, weight loss
risk of foot/leg amputations
c/i GFR <30
191
Q

empagliflozin

A 
Jardiance
SGLT2 - inc glucose excretion
T2DM
s/e: yeast/genital infections, pyelonephritis, AKI, ketoacidosis, weight loss
risk of foot/leg amputations
c/i GFR <30
192
Q

dulaglutide

A

Trulicity - dosed weekly
GLP-1 agonist - inc insulin secretion, dec glucagon secretion, slows gastric emptying
T2DM
s/e: weight loss

193
Q

albiglutide

A

Tanzeum - dosed weekly
GLP-1 agonist - inc insulin secretion, dec glucagon secretion, slows gastric emptying
T2DM
s/e: weight loss

194
Q

argatroban

A

anticoagulant
direct thrombin inhibitor
drug of choice w/ history of HIT

195
Q

aprepitant

A

Emend
NK1 antagonist
delayed CINV (1-7 days after chemo) in mod/high emetic risk

196
Q

vilazodone

A

Viibryd
SSRI + 5HT1 agonist
depression, anxiety
do not use w/ MAOi (phenelzine, tranylcypromine, isocarboxazid)

197
Q

vortioxetine

A

Trintellix
SSRI, 5HT1 agonist
depression, anxiety
do not use w/ MAOi (phenelzine, tranylcypromine, isocarboxazid)

198
Q

timolol

A

Timoptic
beta-blocker - reduces aqueous humor production
glaucoma
s/e: burning, stinging, vision change
do not use timolol in pts with asthma, COPD, bronchitis, cardiac disease

199
Q

mirabegron

A

Myrbetriq
beta-3 agonist
overactive bladder
s/e: hypertension

NAPLEX (20 decks)

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