Tooth Development Flashcards

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1
Q

what are the 3 primary embryonic layers?

A

ectoderm, mesoderm and endoderm

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2
Q

what is tooth enamel derived from?

A

ectoderm

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3
Q

what are all tooth structures apart from the enamel derived from?

A

ectomesenchyme

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4
Q

what is the ectomesenchyme?

A

part of the neural crest that develops beside the primitive nervous system (ectoderm)

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5
Q

what do teeth develop from?

A

tooth germs

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6
Q

what is another name for the neural crest?

A

ectomesenchyme

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7
Q

what is developed in the intiation stage?

A

dental lamina

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8
Q

what are the 5 different stages of tooth development?

A

initiation, morphogenesis, cytodifferentiation, matrix secretion, root formation

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9
Q

name in order of first to last the parts of tooth that are developed

A

dental lamina - bud - cap - bell - erupting tooth - bone

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10
Q

when does the primary epithelial band develop?

A

approximately 6 weeks

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11
Q

what does the primary epithelial band appear as?

A

thickening in epithelium of embryonic mouth (stomodaeum)

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12
Q

when does the dental lamina develop?

A

approximately 7 weeks

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13
Q

what does the primary epithelial band divide into?

A

vestibular lamina and dental lamina

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14
Q

what does the vestibular lamina form?

A

buccal sulcus

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15
Q

what does the dental lamina form?

A

enamel organ

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16
Q

what develops at the morphogenesis stage?

A

bud and cap

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17
Q

when does the enamel bud develop?

A

8-10 weeks

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18
Q

what happens during the bud stage?

A

dental lamina thickens into an enamel bud and the dental papilla appears

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19
Q

when does the enamel cap develop?

A

11 weeks

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20
Q

what happens during the cap stage?

A

enamel organ forms a cap over the papilla and the external enamel epithelium and internal enamel epithelium meet at the cervical loop

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21
Q

what develops during cytodifferentation?

A

bell

22
Q

when does the bell develop?

A

14 weeks

23
Q

what happens during the bell stage?

A

there are more cell layers differentiated and tooth shape is being define?

24
Q

what are the 4 layers of enamel organ at the bell stage?

A

internal enamel epithelium, stratum intermedium, external enamel epithelium and stellate reticulum

25
Q

what happens at 12 weeks?

A

an extension appears on the lingual side of the dental lamina - this is the dental lamina of the permanent tooth

26
Q

what develops during matrix secretion?

A

the eruption of the tooth

27
Q

when does the late bell stage take place?

A

18 weeks

28
Q

what does the late bell stage look like?

A

crown shape is well defined, apposition of enamel and dentine begins

29
Q

what develops into odontoblasts?

A

dental papilla cells adjacent to the IEE

30
Q

what do odontoblasts do?

A

lay down dentine matrix

31
Q

what forms enamel?

A

ameloblasts

32
Q

what happens during dentinogenesis?

A

odontoblast differentiation from IEE, deposition of dentine matrix, mineralisation of dentine

33
Q

what is unmineralised dentine called?

A

predentine

34
Q

how is enamel formed?

A

first the protein matrix is deposited (partially mineralised) and then the organic part is removed and mineralisation is completed (maturation)

35
Q

what happens during ameloblast differentiation?

A

dentine induces IEE cells to differentiate into ameloblasts which elongate becoming columnar and the nucleus migrates to the basal end of the cell

36
Q

what happens during the secretory phase of amelogenesis

A

ameloblasts become secretory cells which synthesise and secrete the enamel matrix proteins. the matrix is then partially mineralised

37
Q

what happens during the maturation phase of amelogenesis?

A

most of the matrix proteins are removed, mineral content of enamel is increased, mature enamel is 95% mineral

38
Q

what happens during the protection phase of amelogenesis?

A

ameloblasts regress to form a protective layer - the reduced enamel epithelium. Eruption takes place and formation of epithelial attachment

39
Q

what is root shape define by?

A

the apical growth of the cervical loop

40
Q

when in root formation what is the cervical loop now called

A

Hertwig’s epithelial root sheath

41
Q

what is hertwig’s epithelial root sheath?

A

2-cell-layered structure

42
Q

what does HERS induce?

A

formation of root dentine

43
Q

what happens once the initial layer of root dentine is formed?

A

HERS breaks up

44
Q

what do the remnants of HERS appear as once they are broken up?

A

debris of malassez which may develop into a cyst

45
Q

what differentiates into cementoblasts?

A

mesenchymal cells from the follicle

46
Q

what do cementoblasts form?

A

cementum

47
Q

what are Sharpey’s fibres?

A

fibres from the developing PDL

48
Q

name the type of tissue, origin and products of the enamel organ?

A

epithelium, ectoderm, enamel

49
Q

name the type of tissue, origin and products of the dental papilla?

A

ectomesenchyme, neural crest, dentine and pulp

50
Q

name the type of tissue, origin and products of the dental follicle?

A

ectomesenchyme, neural crest, cementum and PDL and part of the alveolar bone

51
Q

what is hypodontia?

A

less teeth than you’re supposed to have

52
Q

what is supernumerary?

A

an extra tooth