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OSCE > to review before osce > Flashcards

to review before osce Flashcards

1
Q

What class Pivmecillinam is?

A

Extended-spectrum penicillin antibiotic

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2
Q

What class Amphotericin is?

A

anti-fungal

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3
Q

Mechanism of action of MAO inhibitors

A

–Increased NA and 5HT presynaptic concentrations

–‘Sympathetic surge’

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4
Q

Significant interactions of MAO inhibitors and what other drugs (3)

A

–Tyramine containing foods

–Other drugs:

  • SSRIs
  • Sympathomimetics
  • Sumitriptan
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5
Q

Phenelzine - class

A

monoamine oxidase inhibitor (MAOI)

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6
Q

Antibiotic with Pseudomonas cover (IV)

A

Piperacillin/tazobactam (Tazocin)

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7
Q

Rabeprazole - class

A

PPI

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8
Q

Co-Trimoxazole

  • components (2)
  • class
A
  • trimethoprim and sulfamethoxazole
  • class: sulfonamides
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9
Q

Linezolid

  • class
  • use
  • MoA
A

Class: oxazolidinone

  • Use: treatment of infections caused by multi-resistant bacteria including streptococcus and methicillin-resistant Staphylococcus aureus (MRSA)
  • MoA: inhibiting the initiation of bacterial protein synthesis
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10
Q

Fidaxomicin

  • class
A

macrocyclic antibiotic

*narrow spectrum

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11
Q

Patient on Warfarin is started on antibiotics - what do we need to do?

A

Monitor INR more closely

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12
Q

What type of organisms would gentamycin cover?

A

gram negative

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13
Q

What organisms would Clarithromycin cover?

A
  • a variety of Gram-positive and Gram-negative bacteria
  • Mycoplasma
  • Chlamydia
  • mycobacteria
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14
Q

When prescribing antibiotic, what (2) components of prescription chart do we need to think of?

A
  • indication
  • stop date
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15
Q

Simvastatin and antibiotics, what do we do?

A

Simvastatin may be stoped for a time being

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16
Q

Antibiotics with similar bioavailability via the oral & IV route include (7)

A
  • Levofloxacin 99-100%
  • Metronidazole 99-100%
  • Ciprofloxacin 70-80%
  • Linezolid 99-100%
  • Rifampicin 99-100%
  • Co-trimoxazole 99-100%
  • Clarithomycin
17
Q

When to review antibiotics?

A
  • first Start SMART
  • then focus at 48-72 hours
18
Q

What are indications for switching a patient from IV -> oral antibiotics? (6)

A
  • Haemodynamically stable
  • Apyrexial
  • Clinically improving
  • Able to take oral medications
  • Functional GI tract with no malabsorption problems
  • Not suffering from high-risk infections
19
Q

Antibiotics that may be used for UTI

A
  • Tazocin
  • Cefalexin
  • Amoxicillin
  • Ciprofloxacin
  • Trimethoprin – dose adjustments required for longer courses if CrCl <30ml/min
20
Q

What group of antibiotics should be avoided in epileptic pt?

A

Quinolones

21
Q

(2) side effects of ciprofloxacin

A
  • QT prolongation
  • tendonitis

OSCE (13 decks)

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