Tissues 11 - Hair and Nails Flashcards

Hair: summarise the structure and function of hair, recall the development and structure of the hair follicle, and summarise the regulation of hair growth Nails: summarise the functions, structure and growth of nails

1
Q

Where is hair found?

A

Over the entire surface of the skin, except the glaborous skin of palms, soles, glans penis and vulval introitus.

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2
Q

What are the functions of the hair?

A
  • Protection - against UV light, eyelashes protect the eyes.
  • Sensation - sensory innervation is present within the follicles
  • Thermoregulation
  • Communication/sexual attraction.
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3
Q

List the three types of hair

A
  • Lanugo
  • Vellus
  • Terminal
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4
Q

Describe lanugo hairs and where they are found.

A

Lanugo hairs are fine and long, formed in the foetus at 20 weeks. Usually shed before birth - seen in premature babies and anorexic patients.

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5
Q

Describe vellus hairs and where they are found.

A

Vellus hairs are short, fine and light coloured, and cover most of the body.

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6
Q

Describe terminal hairs and where they are found.

A

Terminal hairs are longer, thicker and darker, found on the scalp, eyebrows, eyelashes, pubic, axillary (armpit ) and beard areas.

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7
Q

How is differentiation of a terminal hair from a villus hair stimulated?

A

Stimulated by androgens at puberty.

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8
Q

Describe the structure of the pilo-sebacious unit.

A
  • Hair follicle is an invagination containing a hair.
  • Upper section, below the sebaceous gland, is the infundibulum.
  • Hair shaft includes an outer cuticle (keratinocytes) and an inner medulla
  • Germinative cells in the hair bulb with melanocytes (synthesise pigment)
  • Arrector pilli muscle - under autonomic control, not easily seen in humans.
  • Sebaceous glands are associated with follicles, and produce sebum.
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9
Q

How is sebum production in adults and children different?

A

Adults have larger, swollen sebaceous glands, activated by androgens in puberty. They produce an oily sebum

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10
Q

Describe the type of secretion that occurs in sebum production.

A

Holocrine secretion - cells disintegrate and release their lipid cytoplasm.

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11
Q

Describe hair embryology.

A
  • Hair follicle has input from the epidermis
  • Epidermis also responsibe for matrix cells, hair shafta dn the dermis
  • Contributes to papilla, blood vessels and nerves.
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12
Q

Describe the hair growth cycle.

A
  • Rate of growth differs between sites - eyebrow hairs grow faster than scalp hair.
  • 3 phases - anagen, catagen and telogen
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13
Q

What is the anagen phase of the hair growth cycle?

A

Growing phase

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14
Q

How long does anagen last in scalp hair compared with eyebrows?

A

3-7 years in scalp hair, 4 months in eyebrows.

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15
Q

What is the catagen phase of the hair growth cycle?

A

Resting phase. When the syntesis of proteins stops, the follicle retreats towards the surface.

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16
Q

How long does resting phase last?

A

3-4 weeks

17
Q

What is the telogen phase of the hair growth cycle?

A

Shedding phase.

18
Q

How is telogen phase in hair growth distinguished?

A

By hairs with a sort club root.

19
Q

What percentage of hairs are in anagen pase, catagen phase and telogen phase at one point in time?

A

Anagen - 80-90% of scalp hairs
Catagen - 10-20% of scalp hairs
Telogen - less than 1% of hairs

20
Q

How many scalp hairs are shed a day?

A

50-100

21
Q

What is the nail?

A

A phylogenetic remanant of claws, which consists of a plate of densely packed keratin.

22
Q

What is the function of nails?

A

To facilitate grasping and tactile sensitivity, and to protect the finer/toe tip.

23
Q

What is the nail matrix?

A

The area beneath the nail where dividing cells keratinize, mature and form the nail plate.

24
Q

What is the nail plate?

A

The nail - 0.3-0.5mm thick, grows 0.1mm a day in fingernails.

25
Q

What is the nail bed?

A

The area beneath the center of the nail, which prodces small amounts of keratin to become adherent to the nail plate.

26
Q

What are the adjacent dermal capillaries and the nail lunulas colours?

A
  • Adjacent dermal capillaries are pink

- White lanula is the visible part of the matrix - the halfmoon

27
Q

What is the hyponychium?

A

The thickened epidermis that underlies the free margin of the nail. (At the top of the nail)