Tissue Renewal and Repair Flashcards
The restoration of tissue architecture and function after an injury is referred to as __________.
Repair
The two main types of reactions involved in tissue repair are __________ and __________.
Regeneration, Connective tissue deposition (scar formation)
Scar formation occurs when tissues are incapable of __________ or if the supporting structures are severely damaged.
Complete restitution
The ability of tissues to repair themselves is determined by their intrinsic __________ capacity.
Proliferative
Tissues that continuously divide and regenerate after injury are classified as __________ tissues.
Labile
The process of new blood vessel development from existing vessels during tissue repair is called __________.
Angiogenesis
Growth factors such as __________ and __________ play a significant role in stimulating angiogenesis.
VEGFs, FGFs
In scar formation, fibroblasts deposit __________ to provide structural stability.
Collagen
The transition from granulation tissue to a mature scar involves the remodeling of __________.
Connective tissue
The healing process that involves epithelial regeneration with minimal scarring is known as __________.
Healing by first intention (primary union)
In the second week of wound healing, there is continued accumulation of __________ and proliferation of __________.
Collagen, Fibroblasts
Labile tissues include __________ cells in the bone marrow and __________ epithelia in the skin.
Hematopoietic, Surface
Stable tissues, such as the __________, can proliferate in response to injury but are normally in a quiescent state.
Liver
The majority of neurons and cardiac muscle cells are classified as __________ tissues.
Permanent
Chronic wounds, such as venous leg ulcers and pressure sores, are examples of defects in __________.
Healing