Tight Junctions Of Epithelial Tissue

Question 1

Name the junctions in the epithelial tissue

Answer 1

From top to bottom

Zonula occludens
Zonula adherents
Desmosome
Gap junction
Hemidesmosome

Question 2

What are the proteins that can be found in zonula occludens?

Answer 2

Membrane proteins: occludin, Claudin
Cytoplasmic proteins: ZO-1, actin, etc

Question 3

What are the proteins in zonula adherens?

Answer 3

Alpha-actinin, vinculin
Actin
Cadherins

Question 4

How wide is the intercellular space in zonula adherens?

Answer 4

15nm

Question 5

How wide is the intercellular space of desmosome/macula adherens?

Answer 5

25nm

Question 6

What does the desmosome contain?

Answer 6

Transmembrane proteins: Desmocollin and desmoglein

Intermediate filaments

Question 7

What does hemidesmosome contain?

Answer 7

Plaque contains BP 200
Transmembrane proteins: alpha 6 integrin, beta 4 integrin, and BP 180

Type VII collagen

Question 8

How wide is the gap junction?

Answer 8

2nm wide but the channel is 1.5nm

Question 9

What does the gap junction contain?

Answer 9

Coupled connexons: contains 6 connexins