Cell Division

Question 1

What is steady state?

Answer 1

of newly originated cells by the stem cells are equal to the # of dead cells on the surface of the epithelium

Question 2

What is the turnover time?

Answer 2

Time required to change the whole population of epithelial cells (30 days)

Question 3

What is radioautography?

Answer 3

Means to study the turnover of epithelial cells and other types of cells

Question 4

What are the three behaviours of an adult cell?

Answer 4

1. Static growth (neurons, skeletal muscle)
2. Expanding (liver)
3. Renewing (epidermis and most epithelia)

Question 5

What are the phases of the cell cycle?

Answer 5

G1: presynthesis of DNA, 25 hours, 2n
S: synthesis of DNA, 8 hours
G2: post DNA duplication, 3 hours, 4n
Mitosis: 2.5 hours (2n is restored)

Question 6

How many chromosomes does a human have?

Answer 6

23 pairs of homologous chromosomes (46 total)

Question 7

What are the six phases of mitosis?

Answer 7

Preprophase
Prophase
Metaphase
Early anaphase
Late anaphase
Telophase

Question 8

What is preprophase?

Answer 8

Intranuclear condensation of chromosomes

Question 9

What is prophase?

Answer 9

Visualization of chromosomes and mitotic spindle

Question 10

What is metaphase?

Answer 10

Chromosomes are in equatorial plane
Lost of nuclear envelope and nucleolus

Question 11

What is early anaphase?

Answer 11

Longitudinal splitting of chromosomes

Question 12

What is late anaphase?

Answer 12

Migration of chromosomes to the poles

Question 13

What is telophase?

Answer 13

Nuclear restitution, nuclear envelope and nucleolar formation, end of cell division