Bone Flashcards
What is the extracellular matrix in the bone made of?
Calcified material and type I collagen
What cells types can be found in bone?
Osteoprogenitor cell (stem cell)
Osteoblasts
Osteocytes
Osteoclasts
Who makes the extracellular matrix in bone?
Osteoblasts
What is the ground substance made of in bone?
Proteoglycans and glycoproteins
What mineral can be found in bone?
Hydroxyapatite
Because bone is one of the hardest tissues in the body, what do you need to do in order to slice the sample?
Decalcification (5% nitric acid or EDTA treatment)
What are the layers in the gross appearance of the bone?
Spongy bone, compact bone, diaphysis (shaft)
What are the different parts of the compact bone?
Periosteum
Outer circumferential system
Haversian System
Interstitial system
Haversian Canal
Volksmann’s canal
Inner circumferential system
Endosteum
What are the different parts of the spongy bone?
Osteoblasts (surrounding on the outside)
Osteocytes
Osteoclasts
Trabecular (spongy) bone
What cells in the bone has multiple nuclei?
Osteoclasts
