Thyroid stuff Flashcards
Hyperthyroid or hypothyroid?
What is TSH doing?
What is T3 and T4 doing?
lethargy fatigue decreased appetite muscle weakness constipation periorbital edema dry cool skin brittle nails
Hypothyroid
High TSH
Low T3 and T4
Primary Hypothyroidism
what will your TSH be
High
Secondary Hypothyroidism
what will your TSH be
Low or normal
Initially in Hashimoto thyroiditis you become Hyper/hypothyroid and then become what
Hyperthyroid
Then Hypothyroid
3 phases of subacute granulomatous Thyroiditis
“de Quervain”
1) hyperthyroid
2) hypothyroid
3) return to normal
what is another name for Cretinism
Congenital Hypothyroidism
what is a antibody-mediated maternal hypothyrodism
Congenital hypothyroidism
6 ps of congenital hyothyroidism
pot bellied pale puffy faced protruding umbilicus protuberant tongue poor brain development
types of hypothyroid r/t iodine deficiency and too much iodine
Congenital hypothyroidism (caused by maternal deficiency)
Wolff Chaikoff effect (autoregulatory too much iodine)
Primary forms of hypothyroidism
Hashimoto thyroiditis Subacute granulomatous thyroiditis (de Quervain) Reidel thyroiditis Postpartum thyroiditis Congenital Hypothyroidism (Cretinism) Iodine Deficiency Wolff-chaikoff effect Medication related - Lithium
non painful goiter with hypothyroid symptoms
think….
Hashimoto thyroiditis
Hyperactive talking fast Tremors anxiety skin warm moist hair fine and brittle eyelid retraction exaggerated deep tendon reflexes tachycardia systolic HTN A=fib menstrual irregularities waxy, discolored induration of skin (lower legs) muscle weakness gynecomastia in males
Hyperthyroidism
What is TSH in hyperthyroidism
Low
autoimmune condition with goiter exophthalmos high T3, T4 low TSH High TSI antibodies levels
Graves disease
what lab will confirm graves disease
TSI antibody level
what are your TSH, T3 and T4 levels doing in Graves disease
Low TSH
Hight T3, T4
what isotope is used in a Radioactive iodine uptake scan (RAIU)
I23 - radioactive isotope of iodine
Hyperthyroid medication
Thionamides stop thyroid hormone synthesis
- Methimazole
- Propylthiouracil (PTU) (also works on peripheral)
- High initial dose till obtain euthyroid status (free t3, t4 levels normal - then low daily maintenance dose
High TSH
High Free T3 and T4 levels
what could cause
TSH secreting pituitary adenoma
diagnosed CT or MRI
Surgical removal through nose is treatment
what causes unregulated thyroid hormone secretion in Hyperthyroidism
Nodules
(Toxic multinodular goiter)
Toxic Adenoma -single nodule
Toxic multinodular goiter)
Toxic Adenoma -single nodule
treatment
Used iodine 131 for radioiodine therapy
In radioiodine therapy what precautions
do not go around pregnant women or young children for 3 days…your radioactive
Treatment for Thyroid Storm
Beta blockers
Thionamides
Glucocorticoids
Parathyroid hormone and vitamin D work to raise or lower the calcium level
raise
