Thyroid Pharm Flashcards

1
Q

Synthroid

A

Levothyroxine

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2
Q

Levothroid

A

Levothyroxine

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3
Q

Levothyroxine

A

First line for hypothyroid
synthetic T4
Once Daily

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4
Q

Levothyroxine SE

A

Should be taken on empty stomach

Caution in cardiac. Interact w/adrenergic effects or decongestants

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5
Q

Liothyronine

A

Synthetic T3
Short half life = not for routine use hypothyroidism
Avoid in cardiac disease

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6
Q

Liotrix

A

4:1 T4/T3
$$$
Rarely recommended
For hypothyroidism but may cause low TSH

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7
Q

Thyroid USP or Strong

A

Porcine thyroid extract
Protein antigenicity
Not recommended

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8
Q

Methimazole

A

Thionamide

Preferred

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9
Q

Propylthiouracil

A

Thionamide
Safer in pregnancy
But more hepatotoxicity

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10
Q

Thionamide

A

Block iodine organification
Caution in in pregnancy
Best for mild hyperthyroidism or younger patients

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11
Q

Thionamide SE

A

pruritic rash, gastric intolerance, arthralgias,

Agranulocytosis

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12
Q

SSKI

A

Iodides

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13
Q

Lugol’s solution

A

Iodides

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14
Q

Iodides

A

High doses inhibit TH synth
Rarely used alone for hyperthyroid
Initiate after thionamide therapy

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15
Q

Radioactive Iodine

A

Slowly destroys gland for hyperthyroidism
Patients > 21
Contraindicated in pregnancy
80% get hypothyroidism instead

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16
Q

Thyroid Storm

A

Beta Blockers & Hydrocortisone

Sx: fever, flushing, sweating, tachycardia/afib, delirium, coma