Hypo/Pituitary/Gonad Axis

Question 1

Male Negative Feedback H

Answer 1

Testosterone. Keeps hormones in narrow window

Question 2

Female Negative Feedback H

Answer 2

Progesterone & Estradiol

Question 3

Both Neg Feedback H

Answer 3

Inhibin - specific for pituitary

Question 4

Estrone

Answer 4

E1 - in fat. Levels too low to detect

Question 5

Estradiol

Answer 5

E2. Synth in ovaries

Question 6

Estriol

Answer 6

E3. In skin.

Question 7

Testosterone

Answer 7

Anabolic - bones & muscle Androgenic - Puberty, gemetogenesis, 2* characteristics, Libido

Question 8

Progesterone

Answer 8

Makes egg Breast dev/lactation

Question 9

Leydig cell

Answer 9

Around seminiferous tubules. LH responsive. Stimulates conversion Cholesterol to prognenolone = more testosterone

Question 10

Sertoli cell

Answer 10

Contact w/spermatozoa, FSH responsive. W/testosterone from Leydig = gameteogenesis Primary source of inhibin

Question 11

Theca Cells

Answer 11

Ovary by follicles. LH responsive. Produce progesterone & androgens. No aromatase (so can’t make estrogens) so androstenedione diffuse to granulosa

Question 12

Granulosa Cells

Answer 12

Contac w/oogonia. FSH responsive. Can’t convert progesterone to androgens so diffuse to theca.

Question 13

Progestins

Answer 13

21 C

Question 14

Androgens

Answer 14

19 C

Question 15

Estrogens

Answer 15

18 C

Question 16

Testicular Axis

Answer 16

Question 17

Ovarian Axis

Answer 17

Question 18

Cholesterol Molecule

Answer 18

Question 19

Female Cycle Horomone Fluctuations

Answer 19

Question 20

Cholesterol Breakdown

Answer 20