Thyroid Hormone Flashcards

1
Q

What kind of hormone is the thyroid hormone?

A

Amine hormone

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2
Q

What are the different types of hormones?

A

Thyroxine (T4) and triiodothyronine (T3)

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3
Q

What is the thyroid hormone produced by?

A

Thyroid gland

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4
Q

What is the thyroid hormone’s target organs?

A

Almost all tissues

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5
Q

Does the thyroid hormone have anabolic or catabolic effects? Does it increase anything?

A
  • Both anabolic and catabolic
  • increases basal metabolic rate
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6
Q

What are the general effects of thyroid hormones?

A

1) Stimulates basal metabolism by increasing oxidative metabolism and anabolic cell functions
2) Regulates body temperature! Hypothyroidism and hyperthyroidism result in cold and heat intolerance.

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7
Q

What specific actions does the thyroid hormone do to the bone?

A
  • promote chondrocyte differentiation and hypertrophy
  • promote chondrocyte ossification
  • promote osteocyte differentiation
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8
Q

What specific actions does the thyroid hormone do to the muscle?

A
  • promote protein synthesis
  • promote protein degradation
  • promote mitochondria number
  • promote conversion to fast-twitch fibers
  • promote muscle loss
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9
Q

What specific actions does the thyroid hormone do to adipose?

A
  • promote fatty acid oxidation
  • promote lipolysis
  • promote TAG mobilization
  • promote thermogenesis
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10
Q

What is hypothyroidism? What are some symptoms?

A

Caused by underactive thyroid and insufficient thyroid hormones are produced.

Symptoms = increased sensitivity to cold, unexplained weight gain, fatigue, and depression

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11
Q

What is hyperthyroidism? What are some symptoms?

A

Caused by an overactive thyroid and too much thyroid hormones are produced.

Symptoms = increased sensitivity to heat, sudden weight loss, and rapid pounding heartbeat.

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