Thyroid Guidelines Flashcards
How to administer MMI during RAI treatment
Discontinue 2-3 days prior yo therapy and resume 3-7 d after RAI and taper
RAI dose for graves
10-15 mCi
370-555 MBq
When to follow up RAI therapg
1-2 mos
Ft4
Tital t3
Tsh
When to consider readmi nistratoon of RAI
Hyperthyroudidm persistent after 6 mongths
Recommended dose of MMI
If FT4 > ULN
1-1.5 5-10
1.5-2 10-20
2-3 30-40
Recommended initial and maintenance dose of MMI
Initial 10-30daily
Maintenance 5-10 daily
In calculating dose for RAI what should gland weight be multiplied to
50-200 over 24 h % amdinistered activity
Higher doses of ATD armin combindwd with L thyroxine
Block and repalce therapy
KI and ATD dose
38 mg KI wifh 15 mg MMI
Vasculitis in ATDs
Anca positive vasculitus
When to treat subclinical hyperthyroidism
TSH <0.1 Individuals > 65 y age (+) cardiac risk factos Heart diaease or osteoporosis Post menopausal women not on estrogen
Elecations in transaminases 3x above upper limit of normal occur ___ % jn px taking ptu
4%
Duration of MMI as primary therapy for GD
12-18 mos
Then discontinued if TSH and TRAB are normal at that time
Remission in gaves
1 yr after Dc thyroid therapy N tsh ft4 total t3
Discsharging post op grgave spx with Lt4
0.8-1.6 ug/kg
Remeasure 6-8 weeks post op
Burch wartofsky score to start treatment
> 45
ATA high risk histopath
Macroscopic invasion of tumor Kncomplete resection of the tumor Distant meta Post op Tg distant mets Pathologic N1 wuth LN > 3 cn Follicular thyroid Ca with extensive vascular invasion >4 foci
Define biochemical incomplete respinse to theraoy
Nonstimulated Tg values of > 1 ng/mL
TSH stumulates valuze > 10 biochemical i complete response to therapy