DM Flashcards
Primary prevention trial
Rosiglitazone
Dream
Primary prevention trial
Troglitazone
Tripod
Primary prevention trial
Lifestyle
ILS+ P
Dpp
Primary prevention trial
Diet
Exergise
Both
Da Qing
Criteria metabolic syndrome
FBS > 110
Tg > 150
BP 130/85
Waist 40 men 35 women
Waist to hip ratio at risk for dm
> 1 men
>0.8 women
Microalbumiuria seen in T1 Dm ? Yrs
5-15 yrs
Define microalbuminuria
20-200 ug / min or
30-300 mg/24 hrs
UKPDS showed that T2DM has reduction in risk of diabtic retinooathy in px assigned to intensive BP control
34-47%
Found thAt severity and progression of retinopathy were associated wifh overt albuminuria
ABCD
AppropriTe BP control in diabetea
Treatment targets in patients presenting with microalbuminuria
Bp < 135/75
Hba1c <7
Ldl <100
Rule decreAse in HbA1c of 1 improves clnduction velocity by _____
1.3
Aldose reductase inhibitors
Tolrestat
Transketolase activator that reduces tissue AGEs
Imprive peroneal conduction velocity and vibration sensation
MechAnism of glucocort
-
MOA of metformin
- activates AMPK
- inhibits mitochondrial glycogenphosphate degydrogenanae
Recommended fiber intake in Dm
14 g/1000 ml
How much fish per week
2x
Grans of Na recommended
2300 mg/day
Insulin receptor subunit that binds insulin
Alpha subunit
