thyroid cancer and nodules Flashcards

1
Q

what % of solitary thyroid nodules are benign

A

95%

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2
Q

name some benign thyroid tumours (4)

A

cyst, colloid nodule, follicular adenoma, hyperplastic nodule

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3
Q

what are benign thyroid tumours encapsulated by and are they functional/ non functional

A

collagen - nonfunctional

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4
Q

what malignant thyroid nodules are there

A

papillary thyroid carcinoma, follicular carcinoma, medullary carcinoma

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5
Q

what happens to a thyroid mass when you swallow/ stick tongue out

A

it moves

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6
Q

what types of differentiated thyroid cancers are there and what type of prognosis is associated

A

papillary and follicular - good

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7
Q

what is the most common thyroid cancer, how does it spread and where does it commonly spread to

A

papillary carcinoma, spreads via lymphatics –> lungs, bone, liver, brain

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8
Q

what commonly causes papillary thyroid cancer and what is it associated with

A

RADIATION - hashimotos thyroiditis (hypo)

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9
Q

what is the 2nd most common cancer, how does it spread

A

follicular, haematogenous - minimally invasive usually

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10
Q

what commonly causes follicular carcinoma

A

low iodine diet

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11
Q

what is medullary thyroid carcinoma and what is the tumour marker

A

rare tumour of parafollicular cell - calcitonin tumour marker

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12
Q

what types of medullary cancer are there

A

sporadic MTC, familial non MEN, familial MEN2a, hyperparathyroidism

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13
Q

what symptoms are associated with medullary cancer

A

diarrhoea and flushed skin

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14
Q

who typically presents with thyroid lymphoma

A

old lady with history of AUTOIMMUNE hypothyroid and a rapid onset

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15
Q

what is the course of management for thyroid lymphoma

A

biopsy –> steroids –> chemo –> radio

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16
Q

what is the most aggressive thyroid tumour

A

anaplastic

17
Q

what is important to ask about in history

A

radiation, FH and iodine

18
Q

what is the gold standard investigation for thyroid cancer

A

USS fine needle aspiration

19
Q

what is the normal level of TSH

A

0.4-4

20
Q

what does thy2 mean vs thy4-5

A

thy2 = benign, thy4-5 = malignant

21
Q

what are red flags for malignancy (6)

A

new nodule ages <20 or >50, male, growing, >4cm, radiation exposure, vocal cord palsy

22
Q

what is considered a low risk tumour and how to you treat it

A

under 50, <4cm - lobectomy and keel low TSH

23
Q

how do you treat a high risk tumour

A

subtotal/ total thyroidectomy, keep TSH <1

24
Q

what follow up is required after surgery

A

keep low TSH, supplement T3/4, iodine scan, REMNANT ABLATION if needed

25
Q

what is the AMES prognosis criteria

A

Age Mets Extend of primary tumour Size of tumour

26
Q

who is low risk in AMES

A

young/older + no mets

27
Q

who is high risk in AMES

A

mets, >5cm in elderly, capsular invasion