Thyroid and Adrenal Glands Flashcards
Describe the structure of the thyroid gland
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What cells make up the thyroid gland - what do these cells make?
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What is the axis involved with the thyroid
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What are the roles of the hormones produced by the thyroid gland
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What is the active form of the hormone in the thyroid gland
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What element do follicular cells need
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How much of Thyroxine is made
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How much of Triiodothyronine is made
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Describe how the Thyroid hormones are regulated
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What is Hyperthyroidism
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What is Graves’ disease
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What is Thyrotoxicosis
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How is Thyrotoxicosis recognised
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What are the symptoms of hyperthyroidism
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What is Hypothyroidism
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What is Thyroiditis
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What can cause hypothyroidism
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What are the symptoms of hypothyroidism
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Describe the radioiodine uptake test
- examining thyroid gland
- determines speed and scope of absorption go iodine by the thyroid gland
- dose of radioiodine given on empty stomach
- control dose dissolved in cup
- using a gamma counter, activity of isotope absorbed by the gland is measured
8-22% after 2 hrs
15-28% after 4 hrs
25-48% after 24 hrs
Describe the T3 inhibition test
- demonstrates existence of normal pituitary control over the productive of thyroid hormones
- for 10 days, T3 is administered daily
- uptake of I is measured before and after the test
- exogenic T3 suppresses TSH, absorption of radioiodine reduced by 50-100%
- hyperthyroidism - loss of pituitary control, TSH high
Where are the adrenal glands located
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What surrounds the adrenal glands?
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What are the two parts of the adrenal gland
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What hormones are produced by the adrenal gland
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Describe the axis
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What does the adrenal medulla produce- What is the function of this hormone
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What type of hormone is Adr, nAdr
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How are Adr and nAdr released
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What is a difference between Adr and nAdr
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Where does norepinephrine bind to to exert its effect
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What is the adrenal cortex composed of?
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What do the different zonas in the adrenal cortex produce?
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What are the examples of glucocorticoids
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How is cortisol transported in the blood
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How is cortisol metabolised
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What are the physiological actions of Cortisol
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How can anemia occur in relation to Cortisol
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What are the anti-inflammatory effects of cortisol
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Describe how the secretion of cortisol is regulated
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What are the functions of mineralocorticoids
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What is the example of mineralocorticoid
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How does Aldosterone work?
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Where is aldosterone produced?
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What are the functions of Androgens - examples
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What disorder is caused by an overactive adrenal gland
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What disorder is caused by an underactive adrenal gland
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Describe symptoms of Cushing’s syndrome
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Describe symptoms of Addison’s disease
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