Thyroid Flashcards
1
Q
Hypothyroidism
A
- decreased thyroid
- clinical signs
- lethargy, weakness, fatgue, cold intolerance, decreased libido, fat, bradycardia, water intoxication, hyponatremia, shock, coma, hypoventilation
2
Q
Levothyroxine (T4)
A
- treat hypothyroidism
- long half life
- main circulating thyroid hormone
3
Q
Liothyronine
A
- treat hypothyroidism
- available as tablet and powder for injection
4
Q
Liotrix
A
- mixture of T4/T3
- treat hypothyroidism
- cardiac adverse effects
5
Q
Hyperthyroidism/Graave’s Disease
A
Causes
- elevated thyroid
- autoimmune disorder
- IgG ab’s bind and activate TSH on thyroid
- iatrogenic = overzealous T4 supplementation
- Neoplasms
- infection/inflammation of thyroid
Signs:
- hyperactive, insomnia
- heat intolerance, rapid heart rate
- weight loss
- exophtalamos
6
Q
Methimazole
A
- Thioamides
- inhibit TPO organification and iodotyrosine –> block synthesis
7
Q
Radioiodine therapy
A
- pereferrred treatment for most patients
- high uptake by thyroid
- effect by B rays and cell destruction
- 80% will become hypothyroid post treatment
