Thyroid Flashcards
What is the thyroid hormone feedback loop?
Ant. Pituitary stimulates thyroid hormone production & release
If blood levels of TH are low then the hypothalamus release TRH
TRH causes the Ant Pituitary to release TSH
TSH stimulates the thyroid to release TH
High TH levels inhibit the secretion of TRH & TSH
If blood levels of TH are low then the
hypothalamus releases TRH
Hormone Orders IF LOW LEVELS
Thyroid releasing hormone
Thyroid-stimulating hormone
T3 and T4
TRH causes
Anterior pituitary to release TSH
TSH releases what
T3 and T4 from thyroid
High T3 and T4 levels inhibit the secretion
TRH
TSH
TRH
Thyroid releasing hormone
TSH
thyroid-stimulating hormone
Thyroid assessment
physical
Lab work (serum TSH, T3, T4, and free T4)
Ultrasound with bx (remove portion)
Thyroid scan
RAI uptake
If questioning hyperthyroidism/enlarged thyroid,
listen for bruit and audible vibration
Is the thyroid normally palpable?
no, only when enlarged or hyperthyroidism
How do you assess the thyroid?
stand posterior to pt
warn and place hands around the neck
pt swallows - brings it forward to feel for nodules in thyroid
When should you not palpate the thyroid?
pt has Thyroiditis
esp if notice visibly enlarged gland bc palpation triggers release of thyroid hormones
RAI uptake
Radioactive Iodine uptake test
- if low iodine in thyroid with test hypoactive visa versa
RAI uptake contraindications
allergies to shellfish and iodine
Meds need to be withheld
Goiter
abnormal enlargement of the thyroid gland
Goiter occurs with
Hyperthyroidism (too much)
hypothyroidism (too little)
Euthyroidism (correct amount)
T/F: The presence of a goiter does mean the thyroid gland is malfunctioning.
False
Goiter pts c/o
inability to swallow
shirt collars too small
TSH normal
2-10
T4 normal
4-12
T3 normal
70-205
Hypothyroidism lab values
TSH
T3
T4
TSH high
T3 low
T4 low
Hyperthyroidism lab values
TSH
T3
T4
TSH LOW
T3 HIGH
T4 HIGH
TSH is used when monitoring
thyroid replacement therapy
TSH STIMULATES
T3 and T4
T3
accurate meaure of hyperthyroidism
after admin of iodine
Free T4
measures the free unbound thyroxine levels of the bloodstream
Hyperthyroidism
excess of thyroid hormone
Hyperthyroidism results in
Increase BMR, CV, GI & neuromuscular function
Affects metabolism of fats, carbs & proteins
Wt loss & heat intolerance
Hyperthyroidism caused by
Autoimmune rxn (Graves’ disease)
Excess of dose of thyroid replacement
Thyroiditis
Tumor
Thyrotoxicosis
thyroid storm
Assessment of Hyperthyroidism
High Temp, Pulse, Resp. and BP
-clubbing, localized edema
Nervous, tremors
wt loss, hunger
N/V/D
breast enlargement
weakness, fatigue
intolerance to heat
Grave’s disease
S/S of hyperthyroidism is related to
directly increases metabolism and tissue sensitivity to stimulation by the sympathetic nervous system
Graves’ disease s/s
Goiter
Bulging eyes
raised red rash not painful
Hyperthyroidism is prone to
comorbidities
* irregular heartbeats
chest pain
cognition low
excess fatigue**
Hyperthyroidism Mgmt
lifelong antithyroid med
Iodine 131
Thyroidectomy
infertility specialist
Nursing problems with Hyperthyroidism
knowledge deficit
insufficient nutrition (give them frequent small meals with more protein and carbs)
altered sleep patterns
altered body image due to goiter and eye bulging
low CO or endurance
vision changes (dry and shape)
Exophthalmos
bulging eyes
Hyperthyroidism pts have a
high active
can’t sit still
Revved up constantly but tired from overexertion
Hyperthyroid pts should avoid
spicy
high fiber foods
caffeine
decongestants and diet pills
Hyperthyroid pts need to monitor weight loss if and be notified if they
more than 10% of body wt
Hyperthyroidism education
meds
wt and nutrition increased
balance activity and rest (fatigue)
lifestyle changes
Eye exams with drops and protection due to bulging
HOB elevated
Hyperthyroid meds
Methimazole/propylthiouracil (PTU)
PTU goal
inhibits thyroid hormone synthesis
PTU adverse effects
**agranulocytosis
hypothyroidism
PTU contraindications
allergy to thioamides
impaired liver
Pregnancy leads to fetal harm
PTU care
signs of hypothyroidism and hyperthyroidism
Lab work WNL
(PT, INR, CBC, Liver, and Ts)
VS and wt
Do not stop PTU abruptly or
risk of severe HYPERTHYROIDISM
- fever, sore throat, unusual bleeding
PTU should be taken
same time of day
with food
Radioactive Iodine 131 goal
destroy thryoid cells at high doses
Radioactive Iodine 131 adverse effects
radiation sickness
bone marrow suppression
hypothyroid
Radioactive Iodine 131 contraindications
pregnancy
young children
Radioactive Iodine 131 dosage
4-10 PO
Radioactive Iodine 131 TEACHING
baseline and monitor CBC
private toilet and flush twice
Bathe daily and frequent handwashing
disposable utensils
sleep alone and avoid prolonged intimate contact for 3-4 days
separate linens
limit visitors and private room needed
Radioactive Iodine 131 can jar the thyroid when the pt does this so avoid
avoid coughing and expectoration
Strong Iodine solution - NONradioactve goals
reduces iodine uptake, inhibits hormone production
blocks release of T3 and T4
Strong Iodine solution - NONradioactve ADVERSE EFFECTS
iodism
Strong Iodine solution - NONradioactve dosage
2-6 drops TID for 10 days
Iodism
corrosive and toxicity
metallic taste with irritation sore gums, teeth, ulcers, swelling in the upper throat
Strong Iodine solution - NONradioactve mixed with
juice
Strong Iodine solution - NONradioactve mgmt
signs of iodism
VS , WT gain, I&O
under and overdosing
Strong Iodine solution - NONradioactve TEACHING
Dilute medication in juice to help with taste
Avoid foods high in iodine (ionized salt)
Take medication same time each day
Increase fluid intake
Hyperthyroidism in older adults
2x wt loss from anorexia as well
apathy
lassitude
depression
confusion
dysrhythmia to heart failure
exophthalmos less common
Thyrotoxic Crisis aka
Thyroid storm
Causes of thyroid storm
severe infection/stress
manipulation of thyroid gland
Thyroid storm assessment
101.3+ temp
increase HR 130+, HTN
agitation, confusion, seizure
exaggerated s/s of hyperthyroidism
Dx testing of thyroid storm
plus cardiac testing
Tx of Thyroid Crisis
Stabilize Cardiac
beta blockers
O2
Replace fluids and electrolytes - D5NS or D5LR
When stabile = Antithyroid meds PTU, corticosteroids, lithium or iodinated contrast
Calm environment - cold, dark, limits visits, no kids
Thyroiditis
inflammation of thyroid
acute, subacute, chronic
Acute Thyroiditis is caused by
bacteria
fungal
parasite
Acute Thyroiditis s/s
painful
swelling
dysphagia
dysphonia
s/s of hyperthyroidism
Tx of Acute Thyroiditis
antibiotics
fluid replacement
Acute Thyroiditis function
returns after tx
Subacute thyroiditis caused by
granulomatous - viral
Subacute Thyroiditis s/s
low fever
fatigue
swelling
pain
Subacute Thyroiditis s/s
Phases
Phase 1: hyperthyroid (1-3 months)
Phase 2: hypothyroid (9-12 months)
Subacute Thyroiditis Tx
NSAIDs
Beta-blockers in Phase 1 (heart beats)
steroids for swelling
Subacute Thyroiditis function
normal after 12-18 months
Subacute Thyroiditis Miantain good
birth control
because babies pop out more
Chronic Thyroiditis s/s
lymphocytic - autoimmune
Chronic Thyroiditis aka
Hashimoto’s disease
Chronic Thyroiditis s/s
painless
hypothyroid s/s
Chronic Thyroiditis Tx
thyroid replacement
Chronic Thyroiditis function
never returns slowly
Thyroidectomy
tx of choice for thyroid CA and goiters if airway problems
CA surgery may include
modified or radical neck dissection
Radioactive Iodine in Thyroid CA
minimize metastasis
shrink thyroid
Thyroidectomy Pre-op teachings
nutrition soft foods (soups, mash, Jello)
avoid caffeine and stimulants
Thyroidectomy post-op care
head & neck support (pillows, no rocking forward with head to strain the neck, use arms to side for pushing)
HOB for swelling
feeding tubes
incision painful to swallow for 24 hours
Incision & airway: bleeding (anterior and side collarbones), airway obstruction
thyroid hormone: depends on the amount left, if total lifelong thyroid replacement, weaning can occur but usually very slow
Thyroidectomy Post-Op Care
BOW TIE
Bleeding
Open airway: HOB 30, avoid hyperextending
Whisper: laryngeal nerve next to the thyroid to reassess with a small voice
Trache set depends
Incision
Emergency: muscle twitching
Pain meds for thyroidectomy
before eating to ease swallowing of foods
Why do you need to watch for muscle twitching after thyroidectomy?
parathyroid triggered and can go into hypocalcemia
Hypothyroidism
Insufficient T3 & T4 leads to BMR, low heat production
Hypothyroidism Causes
tx of hyperthyroidism - PTU
antibody destruction of thyroid
iodine deficiency
Hypo/Hyper Thyroidism analogy
Hypo - tortoise
Hyper - energizer bunny
Hypothyroidism Assessment LABS
high TSH and lipids
low T4 and T3
Hypothyroidism VS
low BMR, Temp, Pulse, BP
Hypothyroidism ASSESSMENTS
wt gain
dry skin and hair
constipation
lethargic and fatigued
intolerance to cold
mixed edema
Hypothyroidism late s/s
mixed edema
subnormal temp
bradycardia
wt gain
low LOC
thickened skin
cardiac complications
Hypothyroidism mgmt
thyroid replacement (T3 and T4)
Hypothyroidism NURSING Problems
Knowledge deficit: don’t know how or when to meds
low CO, endurance, & temperature
Excess nutrition: fatter
Constipation
Skin integrity: dry (need hydration)
Body image: fat and skin integrity
Hypothyroidism anaesthesiology and sedation meds need to be
minimal dose
-increase risk of oversedation and respiratory compensation
Hypothyroidism meds to caution
sedatives
hypnotics
narctoics
Hypothyroid meds
levothyroxine (Synthroid)
levothyroxine (Synthroid) goal
Synthetic T4 – produces various physiologic effects, including increasing metabolism
levothyroxine (Synthroid) adverse effects
thyrotoxicosis
Extremes; jitters, grumpy, thyroid storm
wt loss too much too quickly
levothyroxine (Synthroid) is dosed in
micrograms
levothyroxine (Synthroid) contraindications
acute MI
CVD
Thyroid storm
levothyroxine (Synthroid) nursing care
Assess vital signs, BP, weight, history of; weight change, diet, energy level, mood, temperature response
Monitor thyroid function test results & glucose levels
Give dose in morning before breakfast
Teach symptoms of thyrotoxicosis
levothyroxine (Synthroid) teaching
Daily lifelong if not mixed edema
report any signs of chest pain, nervousness, tremors, sleeplessness, heat intolerance, & excessive sweating
Do not discontinue medication suddenly
What is the major warning sign for med attention in thyroid storm
chest pain
If Synthroid dose is too low
bradycardia
lethargy
constipation
excessive fatigue and sleeping
If Synthroid dose is too high
irritability
palpations
tachycardia
diarrhea
tremors
insomnia
Hypothyroid clients need
follow up
contact if unplanned wt loss/gain of 5 lbs in a week
avoid sedatives
take in the morning
Mixed edema
severe hypothyroidism
Mixed edema causes
sudden d/c thyroid replacement
acute illness, trauma
Mixed edema assessment
s/s of hypothyroid
edema non pitting
low T4, Na, glucose
High TSH
possible CV collapse and coma
HR less than 50
tongue swells
Myxedema Management
Replace T4
Treat precipitating factors
Respiratory & CV support**
Increase body temperature
Maintain fluid, electrolytes, & acid-base
HIGH flow O2warming blanket
Vasopressors
The nurse is completing a health assessment of a patient with suspected hyperthyroidism. What should the nurse assess the client for?
Anorexia
Tachycardia
Weight gain
Cold skin
Tachycardia
The nurse is evaluating a patient who is taking PTU for hyperthyroidism. Which patient statement indicates the drug is effective?
I have excess energy.
I can sleep at night.
I have lost weight since taking this medication.
I perspire throughout the day w/o exertion.
I can sleep at night.
Following a subtotal thyroidectomy, a patient begins to have tingling in the fingers and toes. What should the nurse do first?
Encourage the patient to flex & extend fingers & toes
Notify the healthcare provider
Assess for thrombophlebitis
Ask the client to speak
Notify the healthcare provider
hypocalcemia factor