Thromboembolism Flashcards
The proximal DVTs are
Femoral
Iliac
Popliteal DVTs
The inherited causes of DVT include
Protein C deficiency
Protein S deficiency
Antithrombin deficiency
Inherited prothrombin mutation
Factor v leiden mutation
Dysfibrinogenemia
What is the most specific symptom of DVT?
Unilateral Edema
The most sensitive test for DVT is ……
Homan’s sign
The physical examinations for DVT include…
1.Unilateral edema
2.Homan’s sign
3.Phlegmasia cerulea dolens or alba( oedema with cyanosis or ischemia)
4.Leg pain not specific at all
5.Superficial thrombopheblitis ( 40%of patients without associated cause is suspected to be DVT)
What percentage of patients with homan’s signs have DVT what percentage doesn’t
30%
50%
Differential diagnosis of DVT include
Cellulitis
Baker’s cyst
Lymphangitis
Leg swelling from paralysis
Muscle strain, or tear
Knee abnormality
The 10 parameters for wall’s score include
Active cancer
Pitting edema
Calf swelling > 3cm in affected leg compared to asymptomatic leg
Localised tenderness along the deep venous system
Entire leg swelling
Collateral superficial vein not associated with varicose vein
Bed ridden >/= 3days major surgery within 4 weeks
History of DVT
Alternative diagnosis as likely as DVT or greater
Paralysis or recent plaster immobilisation of Lower extremities
What is the Wells score grading
High probability >/=3
Moderate probability 1/2
Low probability </=0
What are D-dimers
Fibring fragments found in newly formed clot or degradation pf fibrin in cross-linked fibrin
Monoclonal antibodies is used to differentiate
Fibrin-specific clot from fibrin and fibrinogen
Arterial thromboembolic disorders associated with elevated D- dimer include
Stroke
Myocardial infarction
Acute limb ischaemia
Atrial fibrillation
Intracardiac thrombus
The Diagnostic procedure preffered in a case of possible recurrent DVT is …
Impedance plethysmograph
Compression uktrasonography in DVT shows
Abnormal doppler colour flow
Abnormal compressibility of the vein
Echogenic band
Abnormal changes in diameter during valsva movement